Innovating healthcare for the future

Annual Report 2025

RIKEN IMS

Innovating healthcare for the future

Portrait accompanying the Director's Report

Director's
Report

"Toward a Future of Integrative Medical Sciences"

The year 2025 marked a decisive starting point for the new IMS. It was the first year of RIKEN’s Fifth Mid- to Long-Term Plan, and my first year as Center Director. Keeping these aspects in mind, I approached 2025 as a year devoted to building durable foundations for the future, rather than delivering immediate outcomes...

— Masayuki Amagai, Center Director

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Research Highlights

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Establishing maternal epigenetic information in oocytes figure

Azusa Inoue

Establishing maternal epigenetic information in oocytes

New research from IMS addresses a fundamental question in developmental biology: how maternal epigen…

Reprogramming Pathogenic T Cells into Antigen-Specific Regulatory T Cells figure

Masayuki Amagai

Reprogramming Pathogenic T Cells into Antigen-Specific Regulatory T Cells

A longtime aspiration of immunologists has been to develop safe, autoantigen-specific immunotherapie…

The Asian Immune Diversity Atlas: a multinational single-cell reference atlas of circulating human immune cells figure

Chung Chau Hon, Jay W. Shin

The Asian Immune Diversity Atlas: a multinational single-cell reference atlas of circulating human immune cells

A multinational team of leading genomic scientists has generated a single cell reference atlas of ci…

Precise control of actin cytoskeleton assembly with blue light figure

Makito Miyazaki

Precise control of actin cytoskeleton assembly with blue light

OptoVCA, a new system developed by IMS investigators, uses light to control actin network assembly a…

At a Glance

Research Laboratories

56

Research Laboratories

Multi-Omics Platforms

9

Multi-omics Units

Research Projects

12

Research Projects

Publications

250+

Publications

Events & Activities

17

Symposiums & Workshops

Personnel

550+

Total Members