Publications

Abdelnaser RA, Hiyoshi M, Takahashi N, Eltalkhawy YM, Mizuno H, Kimura S, Hase K, Ohno H, Monde K, Ono A, Suzu S. Identification of TNFAIP2 as a unique cellular regulator of CSF-1 receptor activation. Life Sci Alliance 8(5), e202403032 (2025)

Abdelnaser RA, Hiyoshi M, Takahashi N, Kimura S, Hase K, Ohno H, Monde K, Ono A, Suzu S. TNFAIP2 increases macrophage response to CSF-1 through multiple effects on CSF-1 receptor. J Leukoc Biol 117(11), qiaf151 (2025)

Abugessaisa I, Konings M, Manabe R, Murphy CM, Kawashima T, Hasegawa A, Takahashi C, Tagami M, Okazaki Y, Eadie K, Lim W, Doyle S, Verbon A, Fahal AH, Kasukawa T, van de Sande WW. Iron regulatory pathways differentially expressed during Madurella mycetomatis grain development in Galleria mellonella. Nat Commun 16(1), 5324 (2025)

Adam H, Gopinath SCB, Kumarevel T, Ashokkumar T, Adam T, Arshad MKM, Mohammed M, Voon CH, Ramli MM, Uda MNA, Fakhri MA, Salim ET. Electro-Sensing Analysis for Parkinson's Disease Biomarker on Dual-Electrode Surface: Complemented by Molecular Docking. Biotechnol Appl Biochem 72, 1694-1707 (2025)

Aiyoshi T, Kakihara T, Watanabe E, Tanaka N, Ogata Y, Masuoka H, Kurokawa R, Fujishiro J, Suda W, Masumoto K. Unique microbial profiles and severity-associated alterations in the peritoneal fluid of children with acute appendicitis. J Infect Chemother 31(8), 102761 (2025)

Akita R, Lysenko A, Boroevich KA, Yokota T, Kawai D, Iizuka R, Tsunoda T, Uemura S. Voltage-matrix nanopore profiling for the discrimination of protein mixtures. Chem Sci 16(40), 18607-18615 (2025)

Akutsu Y, Ota M, Itamiya T, Mori M, Morio T, Yamamoto K, Okamura T, Fujio K. Effect of Epstein-Barr Virus infection on gene regulation in immune cells of patients with Immune-Mediated Diseases. J Autoimmun 150, 103355 (2025)

Arai N, Sugiura Y, Nakajima S, Wada M, Moriyama S, Mimura Y, Niinomi K, Takayama K, Maeda R, Kitada S, Fagarasan S, Tajima M, Boku S, Takebayashi M, Kato J, Kitago M, Kitagawa Y, Takahashi T, Shimizu H, Uchida H, Suematsu M, Mimura M, Noda Y. Prediction of postoperative delirium by blood metabolome analysis. J Psychiatr Res 184, 500-514 (2025)

Ariga K, Rezki M, Suzuki-Nagata K, Mikawa T, Tsujimura S. MOF-based hybrid electrodes for multi-enzyme cascade reactions with stabilized mediator immobilization. Chem Commun (Camb) 61(66), 12309-12312 (2025)

Asami S, Ohno H. APOL proteins tune gut immunity via commensal lipid recognition. Cell Res (2025)

Asamitsu S, Iwasaki YW. Biomolecular liquid-liquid phase separation associated with repetitive genomic elements. Polym J 57, 785-797 (2025)

Banno A, Mizuno K, Sakamoto M, Komatsubara S, Shirane K, Hayashi K, Hamazaki N, Imami K, Yonemura S, Ishiuchi T. A simple, efficient, and scalable method to generate oocyte-like cells in vitro. Life Sci Alliance 9(2), e202503379 (2025)

Bhak Y, Raptis V, He Y, Nakanishi T, Macdonald-Dunlop E, Sagiya Y, Morisaki T, Matsuda K, Kanai A, Suzuki Y, Oda Y, Kamatani Y, Namkoong H, Saiki R, Kimura A, Koike R, Ogawa S, Miyano S, Imoto S, Kanai T, Fukunaga K, Okada Y, Mälarstig A, Tenesa A. Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases. Sci Rep 15(1), 31721 (2025)

Blechter B, Wang X, Dai J, Karsonaki C, Shi J, Shiraishi K, Choi J, Matsuo K, Chen T, Hung RJ, Chen K, Shu X, Kim YT, Choudhury PP, Williams J, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Wang J, Seow WJ, Song L, Chang I, Hu W, Chien L, Cai Q, Hong Y, Kim HN, Wu Y, Wong MP, Richardson BD, Li S, Zhang T, Breeze C, Wang Z, Bassig BA, Kim JH, Albanes D, Wong Sm JY, Shin M, Chung LP, Yang Y, Zheng H, Dai H, Yatabe Y, Zhang X, Kim Y, Caporaso NE, Chang J, Ho JC, Daigo Y, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood HD, Kunitoh H, Watanabe S, Miyagi Y, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Machiela MJ, Kim YH, Oh I, Lee VH, Chang G, Chen K, Su W, Chen Y, Seow A, Park JY, Kweon S, Gao Y, Liu J, Schwartz AG, Houlston R, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeböller H, Ji B, Wichmann H, Christiani DC, Rennert G, Arnold SM, Brennan P, McKay J, Field JK, Davies MP, Shete SS, Le Marchand L, Liu G, Andrew AS, Kiemeney LA, Zienolddiny-Narui S, Grankvist K, Cox A, Taylor F, Yuan J, Lazarus P, Schabath MB, Aldrich MC, Jeon H, Jiang SS, Chen C, Hsiao C, Hu Z, Burdett L, Yeager M, Hutchinson A, Hicks B, Liu J, Berndt SI, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Kang CH, Wang W, Xu J, Guan P, Tan W, Yu C, Yang G, Sihoe AD, Choi YY, Park IK, Hung H, Vermeulen RC, Cheng I, Wu J, Tsai F, Chan JK, Li J, Lin H, Liu J, Song B, Sawada N, Yamaji T, Wyatt K, Ma H, Zhu M, Wang Y, Qi T, Li X, Ren Y, Chao A, Iwasaki M, Zhu J, Wu G, Chen C, ScD CC, Yang P, Stevens VL, Fraumeni JF, Lin K, Walters RG, Chen Z, Chatterjee N, Gorlova OY, Amos CI, Shen H, Hsiung CA, Chanock SJ, Rothman N, Kohno T, Lan Q, Zhang H. Stratifying lung adenocarcinoma risk with multi-ancestry polygenic risk scores in East Asian never-smokers. J Natl Cancer Inst djaf272 (2025)

Carvalho T, Fagarasan S, Muramatsu M. Activation-induced cytidine deaminase: The missing piece of many puzzles. Cell 188(24), 6691-6695 (2025)

Chen D, Fasina OB, Lin J, Zeng J, Manzoor M, Ohno H, Xiang L, Qi J. TBG096 Ameliorates Memory Deficiency in AD Mouse Model via Promoting Neurogenesis and Regulation of Hsc70/HK2/PKM2/LAMP2A Signaling Pathway. Int J Mol Sci 26(6), 2804 (2025)

Chida K, Ishikawa T, Hanai A, Hananoe A, Kashiwagi Y, Hatakeyama H, Sakai S, Mizui M, Matsui I, Nagasu H, Takeuchi Y, Shinzawa M, Yamamoto R, Kimura T, Kawakami E. Rigorous multiple statistical test unveils combinations of preceding diseases at risk for the development of adult nephrotic syndrome. Comput Biol Med 192(Pt B), 110360 (2025)

Cho H, Shiraishi K, Sunami K, Momozawa Y, Yoshida T, Matsumoto S, Matsuda K, Saito M, Goto A, Honda T, Mochizuki A, Torasawa M, Daigo Y, Shimizu K, Kunitoh H, Yoshida Y, Hirata M, Shimada Y, Ueki M, Ono H, Gotoh M, Igawa YS, Tateishi A, Yamaguchi Y, Higashiyama RI, Machida E, Iwasaki M, Kawai Y, Yasuda H, Hamamoto J, Imoto I, Matsushita H, Takata S, Aoi T, Kaneko S, Kuchiba A, Shimomura A, Fukami M, Hattori K, Ozaki K, Asano Y, Consortium NC, Project BJ, Takano A, Kobayashi M, Miyagi Y, Tanaka K, Suzuki H, Yamaura T, Yoshida T, Goto Y, Horinouchi H, Miyazaki Y, Ito H, Nagashima T, Ohtaki Y, Imai K, Minamiya Y, Okubo K, Inazawa J, Shiraishi Y, Tokunaga K, Kamatani Y, Yatabe Y, Goto K, Tsuboi M, Watanabe S, Ohe Y, Murakami Y, Matsuo K, Hamamoto R, Kohno T. Genomic Profiles of Pathogenic and Moderate-Penetrance Germline Variants Associated With Risk of Early-Onset Lung Adenocarcinoma. J Thorac Oncol 20(11), 1626-1638 (2025)

D’Agostino S, Tettey-Matey A, Volpe M, Pierattini B, D’Agostino M, Smělá D, Ansaloni F, Broglia L, Lau P, Peruzzo O, Braccia C, Armirotti A, Scarpato M, Damiani D, Ros G, Di Carlo V, Maniscalco F, Bechara E, Tartaglia GG, Carninci P, Santoro C, Persichetti F, Pandolfini L, Simonetti A, Espinoza S, Zucchelli S, Sanges R, Bon C, Gustincich S. Internal ribosome entry sites enhance translation in trans in antisense non-coding SINEUP and circular RNAs. Nucleic Acids Res 53(15), gkaf788 (2025)

Dang T, Lysenko A, Boroevich KA, Tsunoda T. VBayesMM: variational Bayesian neural network to prioritize important relationships of high-dimensional microbiome multiomics data. Brief Bioinform 26(4), bbaf300 (2025)

Dang W, Muto Y, He F, Takahashi M, Tsuda K, Nagata T, Tanaka A, Kobayashi N, Kigawa T, Peter Güntert P, Shirouzu M, Yokoyama S, Kuwasako K. 1H, 13C, and 15N resonance assignments and solution structure of the CID domain of SR-related- and CTD-associated factor 8 (SCAF8). Biomol NMR Assign 20(1), 7 (2025)

Delobel D, Nishiyori-Sueki H, Nisoli I, Kawaji H, Robbe P, Carninci P, Takahashi H. Protocol for direct cDNA Cap Analysis of Gene Expression for paired-end patterned flow cell sequencing. STAR Protoc 6(1), 103594 (2025)

Deng K, Isobe Y, Tsumagari K, Kato T, Arai H, Imami K, Arita M. 12/15-Lipoxygenase-Derived Electrophilic Lipid Modifications in Phagocytic Macrophages. ACS Chem Biol 20(2), 357-368 (2025)

Doré E, Bérubé È, Greffard K, Morozumi S, Chénard V, Lemaire G, Allaeys I, Lévesque T, Rudkowska I, Brisson AR, Lambeau G, Bertrand N, Boissinot M, Arita M, Bilodeau J, Isabel S, Boilard E. Secretory phospholipase A2-IIA targets bacterial extracellular vesicles to modulate immune signaling. Commun Biol 8(1), 1634 (2025)

Edahiro R, Sato G, Naito T, Shirai Y, Saiki R, Sonehara K, Tomofuji Y, Yamamoto K, Namba S, Sasa N, Nagao G, Wang QS, Takahashi Y, Hasegawa T, Kishikawa T, Suzuki K, Liu Y, Motooka D, Takuwa A, Tanaka H, Azekawa S, Namkoong H, Koike R, Kimura A, Imoto S, Miyano S, Kanai T, Fukunaga K, Uemura M, Morita T, Kato Y, Hirata H, Takeda Y, Doki Y, Eguchi H, Okuzaki D, Sakakibara S, Ogawa S, Kumanogoh A, Okada Y. Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution. Nat Genet 57(8), 1905-1921 (2025)

Enzan N, Miyazawa K, Koyama S, Kurosawa R, Ieki H, Yoshida H, Takechi F, Fukuyama M, Osako R, Tomizuka K, Liu X, Ozaki K, Onouchi Y; BioBank Japan Project; Matsuda K, Momozawa Y, Aburatani H, Kamatani Y, Yamaguchi T, Akazawa H, Node K, Ellinor PT, Levin MG, Damrauer SM, Voight BF, Joseph J, Sun YV, Terao C, Ninomiya T, Komuro I, Ito K. Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population. Nat Commun 16(1), 9680 (2025)

Fujii R, Nagayoshi M, Nakatochi M, Sato S, Tsuboi Y, Suzuki K, Ikezaki H, Nishida Y, Kubo Y, Tanoue S, Suzuki S, Koyama T, Kuriki K, Takashima N, Katsuura-Kamano S, Momozawa Y, Wakai K, Matsuo K. Multi-Trait Polygenic Risk Score, Nongenetic Determinants, and Cardiovascular Disease Death: A Cohort Study of 14 086 Japanese Individuals. J Am Heart Assoc 14(6), e038572 (2025)

Fujiwara T, Hosaka T, Hasegawa-Takano M, Nishimura Y, Tominaga K, Mori K, Nishino S, Takahashi Y, Uchikubo-Kamo T, Hanada K, Maoka T, Takaichi S, Inoue K, Shirouzu M, Yoshizawa S. Carotenoids bind rhodopsins and act as photocycle-accelerating pigments in marine Bacteroidota. Nat Microbiol 10(10), 2603-2615 (2025)

Fukai YT, Kujirai T, Wakamori M, Kanamura S, Yamauchi L, Zeraati S, Morita S, Tanegashima C, Kadota M, Shirouzu M, Kurumizaka H, Umehara T, Kawaguchi K. Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture. Sci Adv 11(47), eadx9282 (2025)

Fukuda K, Ito Y, Amagai M. Barrier Integrity and Immunity: Exploring the Cutaneous Front Line in Health and Disease. Annu Rev Immunol 43(1), 219-252 (2025)

Fukuda K, Ito Y, Amagai M. The Acid Mantle Reimagined: Unveiling the Role of Stepwise pH Zonation in the Stratum Corneum. J Invest Dermatol 145(9), 2147-2152 (2025)

Fukushima HS, Takeda H. Coordinated action of multiple active histone modifications shapes the zygotic genome activation in teleost embryos. Nat Comm 16(1), 5222 (2025)

Fukushima-Nomura A, Kawasaki H, Amagai M. Integrative omics redefining allergy mechanisms and precision medicine. Allergol Int 74(4), 514-524 (2025)

Fukushima-Nomura A, Kawasaki H, Yashiro K, Obata S, Tanese K, Ebihara T, Saeki H, Etoh T, Hasegawa T, Yazaki J, Seita J, Ohara O, Sekita A, Miyai T, Ashizaki K, Koseki H, Sakurada K, Kawakami E, Amagai M. An unbiased tissue transcriptome analysis identifies potential markers for skin phenotypes and therapeutic responses in atopic dermatitis. Nat Commun 16(1), 4981 (2025)

Funakoshi K, Koike T, Ise W, Tai Y, Narazaki M, Kumanogoh A, Inoue T, Kurosaki T. TACI is required for the survival of short- and long-lived plasma cells. Int Immunol dxaf067 (2025)

Furukawa R, Tozaki T, Mizukami K, Iwasaki Y, Kawate K, Kikuchi M, Ishige T, Momozawa Y, Fukui E, Kakoi H. Mutation rate and spectrum of germline de novo mutations in a closed population of Thoroughbred horses. J Equine Vet Sci 154, 105682 (2025)

Furukawa T, Hara M, Nishida Y, Tanaka K, Shimanoe C, Iwasaka C, Otonari J, Ikezaki H, Nagayoshi M, Tamura T, Tamada Y, Okada R, Oze I, Ito H, Michihata N, Nakamura Y, Tanoue S, Koriyama C, Suzuki S, Otani T, Watanabe I, Tomida S, Kuriki K, Takashima N, Kadota A, Ishizu M, Watanabe T, Nakatochi M, Momozawa Y, Wakai K, Matsuo K. Comparison of polygenic risk scores for type 2 diabetes developed from different ancestry groups. NPJ Metab Health Dis 3(1), 17 (2025)

Furutani M, Fukunaga K, Mushiroda T, Shigemizu D. Identification of a Risk Allele at SLC41A3 and a Protective Allele HLA-DPB1*02:01 Associated with Sarcopenia in Japanese. Gerontology 71(5), 376-387 (2025)

Fuse Y, Murphy SN, Ikari H, Takahashi A, Fuse K, Kawakami E. Artificial intelligence in clinical data analysis: A review of large language models, foundation models, digital twins, and allergy applications. Allergol Int 74(4), 499-513 (2025)

Futakuchi T, Furuhashi H, Isshi K, Hara Y, Ono S, Kurokawa R, Takayasu L, Suda W, Sumiyama K. Ex Vivo Analysis of the Effect of Endoscopic Premedications on the Microbiota Profile in Gastric Juice. JGH Open 9(3), e70141 (2025)

Gailhouste L, Furutani Y, Qin X, Higuchi S, Toguchi M, Yanaka K, Watashi K, Wakita T, Kojima S. miRNA-29b-1-5p mediates an antiviral activity by targeting the HBV entry receptor in human hepatocytes. Sci Rep 15(1), 23725 (2025)

Gorochowski TE, Brockhurst MA, Ceroni F, Iwasaki YW, Yachie N. The Japan-UK Synthetic Biology Conference, Spring 2025: Strengthening Global Links to Engineer Biology. ACS Synth Biol 14(6), 1837-1878 (2025)

Goto-Ito S, Kato S, Takahashi M, Sakamoto A, Yamagata A, Lee Y, Ehara H, Sato M, Toyooka K, Ohkuma M, Ito T. Structural analysis of a symbiotic system involving a Nanobdellati archaeon by cryo-electron tomography. J Biochem 179(1), 21-30 (2025)

Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore GD, Sonehara K, Zakeri M, Chen Y, Dilmore AH, Damle N, Baranzini SE, Hightower G, Nakatsuji T, Gallo RL, Langmead B, Okada Y, Curtius K, Knight R. Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data. Nat Commun 16(1), 825 (2025)

Hanawa S, Son A, Kato T, Matsuo Y, Omae T, Omori Y, Yoshikawa K, Yamanegi K, Hirota K, Ohno H, Ogura H, Ishido S, Noguchi K, Kishimoto H. Identification of beneficial symbiont candidates in commensalism as potential oral gatekeepers. Microbiol Spectr 13(10), e0158825 (2025)

Handa M, Takiuchi T, Kawaguchi S, Hon C, Moody J, Okazaki Y, Ozaki K, Horie M, Ohara Y, Doshida M, Takeuchi T, Matsubayashi H, Saji F, Miyake T, Ishikawa T, Ando Y, Komukai S, Kitamura T, Shin JW, Kimura T. Adverse effects of progestin-primed ovarian stimulation: combination of clinical study and single cell analysis. Reprod Biomed Online 51(2), 104833 (2025)

Harada M, Matsumoto T, Yamamoto M, Goda J, Idei A, Ohtaki K, Kojima N, Yoneda N, Miyauchi K, Katsura K, Ikeda M, Hanada K, Ishizuka-Katsura Y, Hosaka T, Hisano T, Kaizuka T, Yamamoto T, Matsuda M, Nakayama M, Sugimoto-Ishige A, Sakuma M, Hashimoto R, Takayama K, Nakayama M, Nguyen CT, Ishigaki H, Itoh Y, Hashizume Y, Yoshida M, Kawaguchi Y, Takeda M, Koseki H, Shirouzu M, Inoue J, Saito T. Monoclonal antibodies against human TMPRSS2 prevent infection by any SARS-CoV-2 variant. iScience 28(9), 113424 (2025)

Hassan KM, Zhao X, Sugano H, Tanaka T. MR-EEGWaveNet: Multiresolutional EEGWaveNet for Seizure Detection from Long EEG Recordings. APSIPA Trans Signal Inf Process 14(1), 1-39 (2025)

Hata Y, Hetherington N, Battenberg K, Hirota A, Minoda A, Hayashi M, Kyozuka J. snRNA-seq analysis of the moss Physcomitrium patens identifies a conserved cytokinin-ESR module promoting pluripotent stem cell identity. Dev Cell 60(13), 1884-1899 (2025)

Hatzikotoulas K, Southam L, Stefansdottir L, Boer CG, McDonald M, Pett JP, Park Y, Tuerlings M, Mulders R, Barysenka A, Arruda AL, Tragante V, Rocco A, Bittner N, Chen S, Horn S, Srinivasasainagendra V, To K, Katsoula G, Kreitmaier P, Tenghe AM, Gilly A, Arbeeva L, Chen LG, de Pins AM, Dochtermann D, Henkel C, Höijer J, Ito S, Lind PA, Lukusa-Sawalena B, Minn AK, Mola-Caminal M, Narita A, Nguyen C, Reimann E, Silberstein MD, Skogholt A, Tiwari HK, Yau MS, Yue M, Zhao W, Zhou JJ, Alexiadis G, Banasik K, Brunak S, Campbell A, Cheung JT, Dowsett J, Faquih T, Faul JD, Fei L, Fenstad AM, Funayama T, Gabrielsen ME, Gocho C, Gromov K, Hansen T, Hudjashov G, Ingvarsson T, Johnson JS, Jonsson H, Kakehi S, Karjalainen J, Kasbohm E, Lemmelä S, Lin K, Liu X, Loef M, Mangino M, McCartney D, Millwood IY, Richman J, Roberts MB, Ryan KA, Samartzis D, Shivakumar M, Skou ST, Sugimoto S, Suzuki K, Takuwa H, Teder-Laving M, Thomas L, Tomizuka K, Turman C, Weiss S, Wu TT, Zengini E, Zhang Y, Ferreira MA, Babis G, Baras A, Barker T, Carey DJ, Cheah KS, Chen Z, Cheung JP, Daly M, de Mutsert R, Eaton CB, Erikstrup C, Furnes ON, Golightly YM, Gudbjartsson DF, Hailer NP, Hayward C, Hochberg MC, Homuth G, Huckins LM, Hveem K, Ikegawa S, Ishijima M, Isomura M, Jones M, Kang JH, Kardia SL, Kloppenburg M, Kraft P, Kumahashi N, Kuwata S, Lee MT, Lee PH, Lerner R, Li L, Lietman SA, Lotta L, Lupton MK, Mägi R, Martin NG, McAlindon TE, Medland SE, Michaëlsson K, Mitchell BD, Mook-Kanamori DO, Morris AP, Nabika T, Nagami F, Nelson AE, Ostrowski SR, Palotie A, Pedersen OB, Rosendaal FR, Sakurai-Yageta M, Schmidt CO, Sham PC, Singh JA, Smelser DT, Smith JA, Song Y, Sørensen E, Tamiya G, Tamura Y, Terao C, Thorleifsson G, Troelsen A, Tsezou A, Uchio Y, Uitterlinden AG, Ullum H, Valdes AM, van Heel DA, Walters RG, Weir DR, Wilkinson JM, Winsvold BS, Yamamoto M, Zwart J, Stefansson K, Meulenbelt I, Teichmann SA, van Meurs JB, Styrkarsdottir U, Zeggini E. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature 641(8065), 1217-1224 (2025)

Higasa K, Kamatani Y, Kawaguchi T, Kawaguchi S, Sakaue S, Yang T, Okada Y, Momozawa Y, Yamaguchi I, Nelson D, Gravel S, Murakami Y, Yamada R, Matsuo K, Yamano Y, Kim C, Seo J, Kubo M, Matsuda F. Whole-genome sequencing of 3135 individuals representing the genetic diversity of the Japanese population. J Hum Genet (2025)

Hikino K, Fukunaga K, Liu X, Terao C, Mushiroda T. Analysis of factors influencing the relationship between voriconazole plasma concentrations and adverse effects in a paediatric population. Br J Clin Pharmacol 91(7), 2020-2027 (2025)

Hikino K, Ozaki K, Liu X, Ishikawa Y, Mushiroda T, Terao C. Unraveling time-dependent genetic components underlying alcohol response. Neuropsychopharmacology 50(11), 1665-1673 (2025)

Hirakawa T, Kato T, Nakanishi Y, Urushiyama D, Miyata K, Baba T, Ohno H, Yasunaga S, Yotsumoto F, Miyamoto S. Proteomic and Metabolomic Analyses of Adipose-derived Mesenchymal Stem Cell Exosomes and Culture Supernatants. Anticancer Res 45(8), 3409-3424 (2025)

Hisamatsu D, Masuoka H, Takeshige-Amano H, Kurokawa R, Ogata Y, Suda W, Hatano T, Asaoka D, Mabuchi Y, Naraoka Y, Sato N, Asada T, Hattori N, Hattori M, Akazawa C. Acetylcholinesterase inhibitors considerably affect the salivary microbiome in patients with Alzheimer's disease. iScience 28(6), 112593 (2025)

Hongen T, Ito T, Qin X, Sone H. Impact of lead (Pb)-induced neurotoxicity on protein synthesis and cellular stress responses in LUHMES cells. J Trace Elem Med Biol 92, 127759 (2025)

Hori T, Katsura K, Miyamoto-Kohno S, Uchikubo-Kamo T, Yonemochi M, Shirouzu M. Structural insights into endogenous agonist selectivity of aminergic receptors from the octopamine β2 receptor. PNAS Nexus 4(12), pgaf376 (2025)

Horii T, Morita S, Hino S, Hino Y, Fukushima HS, Kobayashi R, Kimura M, Nakao M, Mizukami Y, Inoue A, Hatada I. Germline epigenome editing identifies H3K9me3 as a mediator of intergenerational DNA methylation recovery in mice. Nat Commun 16(1), 11200 (2025)

Hoshikawa Y, Shirota N, Tsugawa H, Kimura S, Matsuyama A, Yashiroda Y, Kakeya H, Arita M, Iizumi R, Yoshida M, Nishimura S. Formation of giant ER sheets by pentadecanoic acid causes lipotoxicity in fission yeast. Proc Natl Acad Sci U S A 122(22), e2422126122 (2025)

Ichihara K, Shiraishi T, Chadani Y, Kito Y, Shiraishi C, Hirata M, Takahashi Y, Kobo A, Hatano A, Matsumoto M, Machida K, Imataka H, Toyoda A, Mishiro-Sato E, Nojima T, Ito T, Taguchi H, Nakayama KI, Matsumoto A. eIF2D promotes 40S ribosomal subunit recycling during intrinsic ribosome destabilization. Nucleic Acids Res 53(22), gkaf1322 (2025)

Iinuma T, Kurokawa T, Aoki T, Onodera A, Fukazawa T, Yamada D, Kitahara G, Okoshi M, Yamaguchi M, Okura H, Sasaki S, Sasako Y, Kira S, Sharif J, Tsuchiyama Y, Kobayashi M, Kobayashi N, Horikoshi T, Inaba Y, Hanaoka H, Okamoto Y, Hanazawa T, Koseki H, Motohashi S. Allogeneic iPSC-derived iNKT cells in recurrent head and neck cancer: a phase 1 trial. Nat Commun 16(1), 11666 (2025)

Ikedo A, Aoki R, Sakai H, Saeki N, Yanagihara Y, Moody J, Kojima M, Kouno T, Ando Y, Hino K, Kinoshita T, Carninci P, Shin JW, Hon C, Uezumi A, Kamei Y, Imai Y. Estrogen signaling in PDGFRα+ cells positively regulates cortical bone metabolism via IGFBP5 in female mice. JBMR Plus 10(1), ziaf178 (2025)

Imaeda K, Tamura T, Nagai S, Sugihara E, Yamasaki J, Otsuki Y, Nakamura K, Takeda T, Nakamura K, Nogami Y, Tsuji K, Chiyoda T, Kisu I, Kobayashi Y, Banno K, Yamaguchi R, Sakurada K, Saya H, Aoki D, Ahmed AA, Nagano O, Masuda K, Yamagami W. LCN2-mediated ferroptosis resistance in tissue homeostasis and early-stage tumorigenesis of the fallopian tube epithelium. iScience 28(6), 112654 (2025)

Imami K. Proteome analysis of puromycin-labeled nascent polypeptides. Methods Enzymol 719, 1-23 (2025)

Inamo J, Takeshita M, Suzuki K, Tsunoda K, Usuda S, Kuramoto J, Moody J, Hon C, Ando Y, Sasaki T, Yoshitake K, Mitsuyama S, Asakawa S, Kanai Y, Takeuchi T, Kaneko Y. Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjögren's disease reveals common and distinct immune activation and fibroblast-mediated inflammation. Nat Commun 16(1), 8299 (2025)

Ise W, Koike T, Shimada N, Yamamoto H, Tai Y, Shirai T, Kawakami R, Kuwabara M, Kawai C, Shida K, Inoue T, Hojo N, Ichiyama K, Sakaguchi S, Shiroguchi K, Suzuki K, Kurosaki T. KLF2 expression in IgG plasma cells at their induction site regulates the migration program. J Exp Med 222(5), e20241019 (2025)

Ishigaki K. Big Data Science on T Cell Receptor-mediated Immune Regulation. JMA Journal 8(2), 338-344 (2025)

Ishiguro K, Fujimura A, Shirouzu M. Structural insights into tRNA recognition of the human FTSJ1-THADA complex. Commun Biol 8(1), 893 (2025)

Ishiguro K, Midorikawa K, Shigi N, Kimura S, Liiv A, Yokoyama T, Ito T, Shirouzu M, Remme J, Miyauchi K, Suzuki T. Hypoxia-induced ribosomal RNA modifications in the peptidyl-transferase center contribute to anaerobic growth of bacteria. Mol Cell 86(1), 78-96 (2025)

Ishihara T, Tsugawa H, Iwanami S, Chang J, Minoda A, Arita M. Transcriptomic and lipidomic analysis of aging-associated inflammatory signature in mouse liver. Inflamm Regen 45(1), 13 (2025)

Ishikawa T, Shinoda M, Oya M, Ashizaki K, Ota S, Kamachi K, Sakurada K, Kawakami E, Shinkai M. Explainable Machine Learning Framework for Dynamic Monitoring of Disease Prognostic Risk: Retrospective Cohort Study. JMIR Form Res 9, e65585 (2025)

Ito E, Hayashizaki R, Hosaka T, Yamane T, Miyata J, Isobe Y, Arita M. Eosinophils and pleural macrophages counter regulate IL-33-elicited airway inflammation via the 12/15-lipoxygenase pathway. Front Immunol 16, 1565670 (2025)

Ito M, Yan Y, Satoh-Takayama N. Functional diversity and tissue-specific regulation of Group 2 innate lymphoid cells in barrier immunity. Int Immunol dxaf062 (2025)

Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T. Structural insights into the role of eIF3 in translation mediated by the HCV IRES. Proc Natl Acad Sci U S A 122(49), e2505538122 (2025)

Iwasaki YW, Shoji K, Nakagawa S, Miyoshi T, Tomari Y. Transposon-host arms race: a saga of genome evolution. Trends Genet 41(5), 369-389 (2025)

Iyer S, Hattori N, Okuda H, Nakagawa T, Fujii S, Maeda T, Koseki H, Ito T. Usp21 Knockout Causes Abnormal Lipid Metabolism in Mouse and Its Polymorphism Correlates with Hypercholesterolemia in Outpatients. Int J Mol Sci 26(19), 9727 (2025)

Izuka S, Komai T, Itamiya T, Ota M, Yamada S, Nagafuchi Y, Shoda H, Matsuki K, Yamamoto K, Okamura T, Fujio K. Integration of transcriptome and immunophenotyping data highlights differences in the pathogenetic kinetics of B cells across immune-mediated disease. RMD Open 11(2), e005310 (2025)

Jhang G, Ueda K, Takeichi H, Remijn GB, Hasuo E. Rivalry between pitch and timbre in auditory stream segregation. PLoS One 20(6), e0323964 (2025)

Jikuya R, Johnson TA, Muraoka E, Noguchi G, Maekawa S, Obara W, Numakura K, Habuchi T, Maejima K, Sasagawa S, Kanazashi Y, Lee H, Song WJ, Sasagawa H, Mitome T, Ohtake S, Kawaura S, Iribe Y, Aomori K, Nagasaka H, Tatenuma T, Ueno D, Komeya M, Ito H, Ito Y, Muraoka K, Kawahara T, Furuya M, Kato I, Hamanoue H, Nishiyama A, Tamura T, Baba M, Suda T, Kodama T, Ogawa T, Uemura H, Yao M, Tsuzuki T, Nagashima Y, Miura Y, Kimura G, Imoto S, Momozawa Y, Fujii S, Makiyama K, Hasegawa T, Shuch BM, Ricketts CJ, Schmidt LS, Linehan WM, Nakagawa H, Hasumi H. Comparative transcriptome atlas as an assistive modality for complex classification of rare kidney cancers. Nat Commun 16(1), 10340 (2025)

Jua S, Lysenko A, Boroevich KA, Sharma A, Tsunoda T. scHDeepInsight: a hierarchical deep learning framework for precise immune cell annotation in single-cell RNA-seq data. Brief Bioinform 26(5), bbaf523 (2025)

Kasamatsu A, Miyahara R, Yoneoka D, Toyo-Oka L, Chiyasirinroje B, Imsanguan W, Suvichapanich S, Yanai H, Wattnapokayakit S, Nedsuwan S, Boonbangyang M, Palittapongarnpim P, Tokunaga K, Mushiroda T, Mahasirimongkol S. One-year mortality of tuberculosis patients on isoniazid-based treatment and its association with rapid acetylator NAT2 genotypes. Int J Infect Dis 155, 107895 (2025)

Kawabata T, Tsuzuki T, Tatsukawa T, Matsui K, Kawakami E. Black-box optimization in immunology and beyond: A practical guide to algorithms and future directions. Allergol Int 74(4), 549-562 (2025)

Kawahara T, Nawa N, Oze I, Ikezaki H, Hara M, Kubo Y, Nagayoshi M, Ito H, Michihata N, Ibusuki R, Suzuki S, Ozaki E, Kuriki K, Takashima N, Katsuura-Kamano S, Nakatochi M, Momozawa Y, Tamura T, Fujiwara T, Matsuo K; J-MICC Study Group. Inverse association between fruit juice consumption and type 2 diabetes among individuals with high genetic risk on type 2 diabetes: the Japan Multi-Institutional Collaborative Cohort (J-MICC) study. Br J Nutr 134(2), 89-96 (2025)

Kawakami E. Artificial intelligence and big data: Reshaping allergy research and patient care. Allergol Int 74(4), 497-498 (2025)

Kawakami E. Dynamic Network Biomarker Analysis Reveals Predisease State in Atopic Dermatitis. J Invest Dermatol (2025)

Kawamura YK, Ozonov EA, Papasaikas P, Kondo T, Nguyen NV, Stadler MB, Smallwood SA, Koseki H, Peters AH. Preventing CpG hypermethylation in oocytes safeguards mouse development. Dev Cell 60(23), 3285-3303.e9 (2025)

Khalil J, Miyauchi K, Suzuki Y, Ki S, Harada Y, Sasaki T, Yamamoto Y, Hashimoto R, Yamamoto T, Matsuda M, Koseki H, Nakayama M, Fukasawa M, Wakita T, Ueno H, Noguchi K, Takayama K, Kubo M. The role of IL-4+ memory T cells in SARS-CoV-2 booster vaccination. Int Immunol dxaf051 (2025)

Kimishima A, Ikeda T, Takahashi O, Naher K, Watanabe C, Takai-Todaka R, Haga K, Honma S, Ujie Y, Uematsu T, Honsho M, Sunazuka T, Honma T, Katayama K, Asami Y. A Dual-Target-Based Screening Strategy for Anti-SARS-CoV-2 Active Compounds Enabling the Identification of Macrocyclic Peptide Natural Products: Chloropeptins. J Nat Prod 88(10), 2351-2359 (2025)

Kimura H, Nagasaki Y, Furukawa S, Ogawa S, Saito T, Terao C, Iwata N, Ikeda M. Genomic architecture of bipolar disorder in Japan: Insights from genomic structural equation modeling. Psychiatry Clin Neurosci 79(12), 859-860 (2025)

Kise M, Shimamura M, Umezawa N, Tanaka N, Da R, Li S, Hosoya T, Saito T, Terao C, Yasuda S. The exacerbating role of Ras guanyl-releasing protein 1 in idiopathic inflammatory myopathies. Clin Immunol 282, 110636 (2025)

Kiuchi M, Nemoto M, Yagyu H, Aoki A, Iwamura C, Sugimoto H, Masuo Y, Morita H, Ma S, Okuno Y, Hishiya T, Tsuji K, Sasaki A, Kokubo K, Ohishi K, Shinmi R, Sonobe Y, Iinuma T, Yonekura S, Yokomizo T, Komatsu N, Onodera A, Okumura S, Ito T, Hatano E, Tsuruyama T, Kurashima Y, Mato N, Suzuki T, Kimura MY, Motohashi S, Kawakami E, Ueno H, Tumes DJ, Hanazawa T, Nakayama T, Hirahara K. Hepatic leukemia factor directs tissue residency of proinflammatory memory CD4+ T cells. Science 390(6778), eadp0714 (2025)

Kiuchi S, Chung MH, Sakai H, Nakaya T, Ohbuchi K, Tsumagari K, Imami K, Otoguro Y, Nitta T, Yamamoto H, Sasaki K, Tsugawa H. Unraveling anti-inflammatory metabolic signatures of Glycyrrhiza uralensis and isoliquiritigenin through multiomics. NPJ Syst Biol Appl 11(1), 145 (2025)

Kobayashi T, Hachiya T, Lu Y, Ikehata Y, China T, Kawano H, Nagata M, Ide H, Isotani S, Nojiri S, Iwami T, Uchiyama S, Okazaki Y, Nakagawa H, Morisaki T, Matsuda K, Kamatani Y, Terao C, Horie S. Local radiotherapy for cancer patients is associated with mosaic loss of chromosome Y, a hallmark of male aging. NPJ Aging 11(1), 69 (2025)

Kock K, Tan L, Han K, Ando Y, Jevapatarakul D, Chatterjee A, Lin Q, Buyamin E, Sonthalia R, Rajagopalan D, Tomofuji Y, Sankaran S, Park M, Abe M, Chantaraamporn J, Furukawa S, Ghosh S, Inoue G, Kojima M, Kouno T, Lim J, Myouzen K, Nguantad S, Oh J, Rayan N, Sarkar S, Suzuki A, Thungsatianpun N, Venkatesh P, Moody J, Nakano M, Chen Z, Tian C, Zhang Y, Tong Y, Tan C, Tizazu A, Loh M, Hwang Y, Ho RC, Larbi A, Ng T, Won H, Wright FA, Villani A, Park J, Choi M, Liu B, Maitra A, Pithukpakorn M, Suktitipat B, Ishigaki K, Okada Y, Yamamoto K, Carninci P, Chambers JC, Hon C, Matangkasombut P, Charoensawan V, Majumder PP, Shin JW, Park W, Prabhakar S. Asian diversity in human immune cells. Cell 188(8), 2288-2306.e24 (2025)

Kohwi Y, Wong X, Grange M, Sexton T, Richards HW, Kitagawa Y, Sakaguchi S, Liang Y, Chuong C, Botchkarev VA, Taniuchi I, Reddy KL, Kohwi-Shigematsu T. Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression. Elife 14, rp105915 (2025)

Koide R, Abe T, Harimoto T, Kamada  AJ, Saito Y, Guerrini  M, Fujii A, Parrish E, Horie  M, Kiyonari H, Yamamoto  K, Tomonaga K, Parrish  NF. Interferon and TLR genes, but not endogenous bornavirus-like elements, limit BoDV1 replication after intracerebral infection. PLoS Pathog 21, e1013165 (2025)

Koide R, Nakashima Y, Kojima S, Sotomi Y, Sakata Y, Sakata Y, Ito K, Parrish NF. Pooled screening for endogenous HHV-6 in subjects with coronary artery disease. Virus Genes 61(2), 239-243 (2025)

Kondo T, Ito S, Takano J, Han Y, Endo T, Kondo K, Shibata M, Kawashima Y, Sugishita H, Harachi M, Sharif J, Seita J, Ohara O, Nakayama M, Koseki H. SKP1A bound to Polycomb-silenced genes mediates degradation of PRC2 and preconditions their activation. Mol Cell 85(17), 3306-3320.e6 (2025)

Konings M, Strepis N, Manabe R, Hasegawa A, Chaudhari S, du Pre S, Schippers M, Tagami M, Ma J, Okazaki Y, Todd M, Biersack B, Masand V, Verbon A, Kasukawa T, Abugessaisa I, van de Sande WW. Kinome analysis of Madurella mycetomatis identified kinases in the cell wall integrity pathway as novel potential therapeutic drug targets in eumycetoma caused by Madurella mycetomatis. PLoS Negl Trop Dis 19(9), e0013482 (2025)

Koromina M, Ravi A, Panagiotaropoulou G, Schilder BM, Humphrey J, Braun A, Bigdeli T, Chatzinakos C, Coombes BJ, Kim J, Liu X, Terao C, O'Connell KS, Adams MJ, Adolfsson R, Alda M, Alfredsson L, Andlauer TF, Andreassen OA, Antoniou A, Baune BT, Bengesser S, Biernacka J, Boehnke M, Bosch R, Cairns MJ, Carr VJ, Casas M, Catts S, Cichon S, Corvin A, Craddock N, Dafnas K, Dalkner N, Dannlowski U, Degenhardt F, Di Florio A, Dikeos D, Fellendorf FT, Ferentinos P, Forstner AJ, Forty L, Frye M, Fullerton JM, Gawlik M, Gizer IR, Gordon-Smith K, Green MJ, Grigoroiu-Serbanescu M, Guzman-Parra J, Hahn T, Henskens F, Hillert J, Jablensky AV, Jones L, Jones I, Jonsson L, Kelsoe JR, Kircher T, Kirov G, Kittel-Schneider S, Kogevinas M, Landén M, Leboyer M, Lenger M, Lissowska J, Lochner C, Loughland C, MacIntyre DJ, Martin NG, Maratou E, Mathews CA, Mayoral F, McElroy SL, McGregor NW, McIntosh A, McQuillin A, Michie P, Mitchell PB, Moutsatsou P, Mowry B, Müller-Myhsok B, Myers RM, Nenadić I, Nievergelt CM, Nöthen MM, Nurnberger J, 'Donovan MO, 'Donovan CO, Ophoff RA, Owen MJ, Pantelis C, Pato C, Pato MT, Patrinos GP, Pawlak JM, Perlis RH, Porichi E, Posthuma D, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Schall U, Schofield PR, Schulze TG, Scott L, Scott RJ, Serretti A, Smoller JW, Świątkowska B, Soler Artigas M, Stein DJ, Streit F, Toma C, Tooney P, Vawter MP, Vieta E, Vincent JB, Waldman ID, Weickert CS, Weickert T, Witt SH, Hong KS, Ikeda M, Iwata N, Won H, Edenberg HJ, Ripke S, Raj T, Coleman JR, Mullins N. Fine-mapping genomic loci refines bipolar disorder risk genes. Nat Neurosci 28(7), 1393-1403 (2025)

Kosugi S, Terao C. TRsv: simultaneous detection of tandem repeat variations, structural variations, and short indels using long read sequencing data. Genome Biol 26(1), 246 (2025)

Koyanagi Y, Murakami Y, Kominami T, Fukushima M, Goto K, Yokota S, Mizobuchi K, Mawatari G, Torii K, Inoue Y, Ota J, Okuda D, Fujiwara K, Yamaga H, Hisai T, Endo M, Iijima H, Kaida T, Miyata K, Nakazaki S, Hayashi T, Hirami Y, Akiyama M, Terao C, Momozawa Y, Sonoda K, Nishiguchi KM, Ikeda Y. Clinical characteristics of EYS-associated retinal dystrophy in 291 Japanese patients. NPJ Genom Med 11(1), 3 (2025)

Kozuka C. Genome-Independent Transmission of Obesity and Type 2 Diabetes Risk: From Gametes to Early-Life Programming. J Biochem mvaf070 (2025)

Kudo Y, Miyamoto K, Suzuki S, Chida A, Tojo A, Hasegawa M, Shigehara A, Koya I, Ando Y, Sato M, Kondo A, Kumagai T, Deguchi H, Sugiyama Y, Ito Y, Shirosaki K, Yamagishi S, Maeda Y, Kanamori H, Kano M, Kato M, Tsujikawa H, Yoshimatsu Y, Takabayashi K, Okabayashi K, Kanai T, Hosoe N, Kato M, Moody J, Hon C, Kuroda T, Yamada Y, Fujino A, Sujino T. Longitudinal single-cell analysis of glucagon-like peptide-2 treatment in the patients with short bowel syndrome. JCI Insight 10(18), e194497 (2025)

Kumagai T, Shimogawara R, Wada A. Molecular containment of iron source inhibits larval survival of Schistosoma mansoni and egg-laying behavior of the female adult worms via ovarian atrophy. Trop Med Health 53(1), 121 (2025)

Kurokawa R, Watanabe K, Ogata Y, Takemine S, Takagi M, Shindo C, Suda W. Complete genome sequences of five Limnohabitans strains isolated from two shallow eutrophic lakes in Japan. Microbiol Resour Announc 14(12), e0094425 (2025)

Kuwana S, Yasuoka Y. Meeting report about self-organization in biology: Freiburg Spemann-Mangold Centennial Symposium. Dev Growth Differ 67(2), 36-42 (2025)

Li B, Sakaguchi T, Tani H, Ito T, Murakami M, Okumura R, Kobayashi M, Okuzaki D, Motooka D, Ikeuchi H, Ogino T, Mizushima T, Hirota S, Otake-Kasamoto Y, Kishikawa T, Nakamura S, Kobiyama K, Ishii KJ, Hashiguchi T, Kawai T, Kuroda E, Shinzaki S, Ise W, Kurosaki T, Kikuchi A, Tomofuji Y, Okada Y, Takeda K, Kayama H. OTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation. Sci Immunol 10(109), eadm6843 (2025)

Li D, Tangtanatakul P, Lei Y, Liu X, Huang H, Lin Y, Li C, Chen Y, Cai L, Zhao J, Pisitkul P, Suangtamai T, Yu J, Zhou Y, Xu Y, Xiao Y, Kunhapan P, Sun R, Yu G, Sun H, Hirankarn N, Ishikawa Y, Terao C, Kim K, Bae S, Wang M, Huang H, Yang W, Wang Y. Imputation disparities driven by recent selection and their impact on disease risk estimation in East and Southeast Asian populations. Commun Biol 8(1), 1822 (2025)

Li T, Zhou G, Zhao X, Zhao Q. Scaling Capability in Token Space: An Analysis of Large Vision Language Model. J Mach Learn Res 26(253), 1-61 (2025)

Lin Y, Li J, Lai Y, Liu T, Chiou J, Lu H, Ariyoshi K, Terao C, Yang J, Chou C, Liang W, Chou I, Ho C, Lin T, Liao C, Huang S, Tsai F. Blood Pressure Genetics in Han Taiwanese With Cross-Trait Analysis in East Asians: Insights Into Comorbidities, All-Cause Mortality, and Cardiovascular Mortality. Hypertension 82(12), 2227-2240 (2025)

Lin Y, Li J, Liu T, Chiou J, Lu H, Ariyoshi K, Uchiyama S, Terao C, Yang J, Chou C, Liang W, Chou I, Lin C, Lin T, Liao C, Huang S, Tsai F. Unraveling the genetic link: causal effects and PRS predictions of adiposity-related health conditions in East Asian individuals. Obesity 33(9), 1765-1778 (2025)

Luginbühl J, Prabhu AV, Yip CW, Ando Y, Leon J, Yasuzawa K, Hon CC, Moody J, Roudnicky F, Kremer T, Shin JW. Defining the Cis-Regulatory Elements of SCN1A in GABAergic Interneurons. Mol Neurobiol 62(12), 15730-15740 (2025)

Maruyama T, Ishikawa D, Kurokawa R, Masuoka H, Nomura K, Haraikawa M, Orikasa M, Odakura R, Koma M, Omori M, Ishino H, Ito K, Shibuya T, Suda W, Nagahara A. Hydrogen Gas Inhalation Improved Intestinal Microbiota in Ulcerative Colitis: A Randomised Double-Blind Placebo-Controlled Trial. Biomedicines 13(8), 1799 (2025)

Maskawa R, Takayasu H, Takayasu L, Suda W, Takayasu M. Stochastic spatiotemporal growth model reproducing the universal statistical laws of the gut microbiome. Phys Rev Research 7(1), 013269 (2025)

Maskawa R, Takayasu L, Takayasu H, Watanabe K, Takemine S, Kakimoto T, Takeshita K, Narushima S, Suda W, Takayasu M. High-resolution fecal pharmacokinetic modeling in mice with orally administered antibiotics. Sci Rep 15(1), 24441 (2025)

Masuda T, Watanabe C, Kato K, Honma T, Ohta M, Ikeguchi M. Quantitative Structure-Activity Relationships for Human Galectin-3 Inhibitors: Insights from Quantum Chemical Interaction Energy Terms. J Chem Inf Model 65(12), 6287-6297 (2025)

Masuo Y, Murakami A, Akamine R, Iri O, Uno S, Murata K, Nishitani K, Ito H, Watanabe R, Fujii T, Iwasaki T, Nakamura S, Kuriyama S, Morita Y, Murakawa Y, Terao C, Okada Y, Hashimoto M, Matsuda S, Ueno H, Yoshitomi H. Stem-like and effector peripheral helper T cells comprise distinct subsets in rheumatoid arthritis. Sci Immunol 10(110), eadt3955 (2025)

Matsumura N, Tsuruta T, Goto-Koshino Y, Mizukami K, Aoi T, Yamada R, Matsumoto Y, Nagao I, Sakamoto M, Nakagawa T, Fukuoka R, Ohmi A, Chambers JK, Uchida K, Momozawa Y, Tomiyasu H. Comprehensive investigation of gene mutations in canine large cell gastrointestinal lymphoma. Front Vet Sci 12, 1535446 (2025)

Matsuoka Y, Katsumata Y, Chu P, Morikawa R, Nakamoto N, Iguchi K, Takahashi K, Kou T, Ito R, Taura K, Yazumi S, Terajima H, Honjo G, Ichihara G, Muramoto Y, Sato K, Maeda R, Hata K, Toriu N, Yanagita M, Tajima M, Fagarasan S, Yamada K, Sugiura Y. Monitoring ferroptosis in vivo: Iron-driven volatile oxidized lipids as breath biomarkers. Redox Biol 86, 103858 (2025)

Mei H, Hayashi R, Kozuka C, Kumon M, Koseki H, Inoue A. H2A.Z reinforces maternal H3K4me3 formation and is essential for meiotic progression in mouse oocytes. Nat Struct Mol Biol 32(10), 1883-1893 (2025)

Metwally H, Elbrashy MM, Kayama H, Okuyama K, Taniuchi I, Takeda K, Kishimoto T. Threonine phosphorylation of STAT1 safeguards gut epithelial integrity and restricts interferon-mediated cytotoxicity. Proc Natl Acad Sci U S A 122(30), e2511957122 (2025)

Miyata J, Sunata K, Sasaki H, Kawashima Y, Otsu Y, Onozato R, Matsuyama E, Okuzumi S, Mochimaru T, Masaki K, Kabata H, Konno R, Ishikawa M, Hasegawa Y, Kimizuka Y, Arita M, Fukunaga K. Multi-omics insights into retinoic acid-mediated regulation of eosinophils in severe asthma. J Allergy Clin Immunol (2025)

Miyauchi E, Taida T, Uchiyama K, Nakanishi Y, Kato T, Koido S, Sasaki N, Ohkusa T, Sato N, Ohno H. Smoking affects gut immune system of patients with inflammatory bowel diseases by modulating metabolomic profiles and mucosal microbiota. Gut 75(1), 46-56 (2025)

Miyauchi E, Yamazaki K, Tsuboi Y, Nakajima T, Ono S, Mizuno K, Takahashi N, Imamura K, Morita H, Miura N, Okuda S, Kikuchi J, Sasaki N, Ohno H, Yamazaki K. Patients with periodontitis exhibit persistent dysbiosis of the gut microbiota and distinct serum metabolome. J Oral Microbiol 17(1), 2499284 (2025)

Mizukami K, Usui Y, Iwasaki Y, Shiraishi K, Hirata M, Kamatani Y, Endo M, Takahashi S, Mochizuki Y, Yamaguchi M, Kohno T, Matsuda K, Sugano K, Yoshida T, Nakagawa H, Terao C, Koyanagi YN, Matsuo K, Murakami Y, Spurdle AB, Momozawa Y. Pan-cancer prevalence, risk, and clinical and demographic characteristics of Lynch Syndrome-associated variants in BioBank Japan. Commun Med (Lond) 5(1), 522 (2025)

Mohri Y, Nie J, Morinaga H, Kato T, Aoto T, Yamanashi T, Nanba D, Matsumura H, Kirino S, Kobiyama K, Ishii KJ, Hayashi M, Suzuki T, Namiki T, Seita J, Nishimura EK. Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma. Nat Cell Biol 27(10), 1647-1659 (2025)

Mukai M, Takahashi H, Kubo Y, Asahina Y, Iriki H, Nomura H, Kamata A, Ito H, Kurebayashi Y, Yamagami J, Mikami N, Sakaguchi S, Amagai M. Conversion of pathogenic T cells into functionally stabilized Treg cells for antigen-specific immunosuppression in pemphigus vulgaris. Sci Transl Med 17(821), eadq9913 (2025)

Munechika K, Ueda K, Takeichi H, Hasuo E, Remijn GB. Filling the blanks of checkerboard speech with noise: Evidence for phonemic restoration and masking. J Acoust Soc Am 158(2), 1308-1316 (2025)

Murakami A, Akamine R, Tanaka S, Murata K, Nishitani K, Ito H, Watanabe R, Fujii T, Iwasaki T, Masuo Y, Iri O, Nakamura S, Kuriyama S, Morita Y, Murakawa Y, Terao C, Okada Y, Hashimoto M, Matsuda S, Ueno H, Yoshitomi H. Human CD4+ T cells regulate peripheral immune responses in rheumatoid arthritis via insulin-like growth factor-like family member 2. Sci Immunol 10(110), eadr3838 (2025)

Murakami K, Takamura S, Kakimi K, Matsumura N. Tumor immunology and immunotherapy for endometrial cancer. Expert Opin Investig Drugs 34(1-2), 37-48 (2025)

Muramatsu W, Maryanovich M, Akiyama T, Karagiannis GS. Thymus ad astra, or spaceflight-induced thymic involution. Front Immunol 15, 1534444 (2025)

Murata Y, Fujisawa M, Watanabe T, Matsubara S, Takase Y, Takahashi T, Namba K, Yamagata A, Terada T. An amino acid transporter in the small intestine mediates basolateral efflux of plant-derived nicotianamine iron complexes. J Biol Chem 301(11), 110731 (2025)

Mushiroda T. Pharmacogenetic biomarkers associated with risk of developing severe drug eruptions and clinical implementation of HLA genetic testing. Allergol Int 74(3), 380–385 (2025)

Nah GS, Matsuo J, Bahirvani AG, Kimura S, Chin DW, Ng P, Koh CP, Mok MM, Wang CQ, Tergaonkar V, Voon DC, Kohu K, Muroi S, Shi J, Yu S, Hossain Z, Liau W, Phuong CT, Sanda T, Marsman J, Horsfield J, Cheroutre H, Chan YH, Pang B, Chong PY, Soong R, Tenen DG, Maekawa Y, Venkatesh B, Ito Y, Taniuchi I, Osato M. An Upstream RUNX3 Enhancer, eR3 (-18m/-28h), Regulates the Development of Gut-Associated Anti-Tumorigenic CD8+CD103+ Cytotoxic T Lymphocytes in Mouse and Human. Genes Cells 30(6), e70052 (2025)

Nakamura K, Yatsuka Y, Naito S, Hasegawa A, Kasukawa T, Kondo A, Kishita Y, Sugiyama Y, Onuki T, Ebihara T, Tsuruoka T, Fushimi T, Ohtake A, Murayama K, Imai-Okazaki A, Okazaki Y. Successful Diagnosis of Sengers Syndrome Using a Comprehensive Genomic Analysis. Mol Genet Genomic Med 13(1), e70048 (2025)

Natsumoto B, Shoda H, Tsuji M, Otsu M, Taniguchi H, Yamamoto K, Fujio K. Identification of Potential Therapeutic Agents for Type I Interferonopathy Using iPSC-Based Disease Modeling. J Clin Immunol 45(1), 140 (2025)

Negi A, Sakamoto R, Ienaga R, Miyazaki M, Maeda YT. Myosin-driven advection and actin reorganization control the geometry of confined actomyosin gel. Nano Lett 25(52), 17979-17987 (2025)

Nemoto S, Uchida K, Kubota T, Nakayama M, Han Y, Koyasu S, Ohno H. Tetraspanin7 in adipose tissue remodeling and its impact on metabolic health. Mol Metab 97, 102168 (2025)

Newman AG, Sharif J, Bessa P, Zaqout S, Brown JP, Richter D, Dannenberg R, Nakayama M, Mueller S, Schaub T, Manickaraj S, Boehm-Sturm P, Ohara O, Koseki H, Singh PB, Tarabykin V. Glial reactivity and cognitive decline follow chronic heterochromatin loss in neurons. Nat Commun 16(1), 7325 (2025)

Niitsu A, Thomson AR, Scott AJ, Sengel JT, Jung J, Mahendran KR, Sodeoka M, Bayley H, Sugita Y, Woolfson DN, Wallace MI. Rational Design Principles for De Novo α-Helical Peptide Barrels with Dynamic Conductive Channels. J Am Chem Soc 147(14), 11741-11753 (2025)

Nishida N, Zhao Q, Shimada I. Bioreactor In-Cell NMR: A Powerful Tool for Observing Intracellular Biological Events. Curr Opin Struct Biol 93, 103086 (2025)

Nishide M, Nishimura K, Matsushita H, Kawada S, Shimagami H, Metsugi S, Kato Y, Kawasaki T, Tsujimoto K, Edahiro R, Shirai Y, Itotagawa E, Naito M, Yamamoto Y, Matsukawa K, Omiya R, Okada Y, Hattori K, Narazaki M, Kumanogoh A. Neutrophil single-cell analysis identifies a type II interferon-related subset for predicting relapse of autoimmune small vessel vasculitis. Nat Commun 16(1), 3581 (2025)

Nishigaya Y, Takase S, Sumiya T, Kikuzato K, Hiroyama T, Maemoto Y, Aoki K, Sato T, Niwa H, Sato S, Ihara K, Nakata A, Matsuoka S, Hashimoto N, Namie R, Honma T, Umehara T, Shirouzu M, Koyama H, Nakamura Y, Yoshida M, Ito A, Shirai F. Discovery of potent substrate-type lysine methyltransferase G9a inhibitors for the treatment of sickle cell disease. Eur J Med Chem 293, 117721 (2025)

Noguchi G, Baba M, Ohtake S, Jikuya R, Mitome T, Kawaura S, Aomori K, Iribe Y, Nagasaka H, Wilan K, Funasaki S, Muraoka E, Fujii S, Tsuzuki T, Kato I, Furuya M, Nagashima Y, Nishizawa H, Kamba T, Kuraoka S, Kawagoe T, Mizuki N, Tatenuma T, Ueno D, Kawahara T, Ito H, Komeya M, Ito Y, Muraoka K, Uemura H, Tamura T, Ogawa T, Suda T, Yao M, Makiyama K, Nakagawa H, Shuch BM, Ricketts CJ, Schmidt LS, Linehan WM, Nishinakamura R, Hasumi H. Genetically engineered human iPS cell-derived kidney organoid recapitulates an early stage of ALK fusion gene-associated renal tumorigenesis. Mol Cancer Res (2025)

Noji M, Sugita Y, Yamazaki Y, Miyazaki M, Suzuki Y. Protein design of two-component tubular assemblies similar to cytoskeletons. Nat Commun 16(1), 6738 (2025)

Nosaka Y, Nagano M, Yabuta Y, Nakakita B, Nagaoka SI, Okamoto I, Sasada H, Mizuta K, Umemura F, Kuma H, Okochi Y, Katou Y, de Massy B, Inoue A, Horie A, Mandai M, Ohta H, Saitou M. Generation of germinal-vesicle oocytes from mouse embryonic stem cells under an ovarian soma-free condition. Dev Cell 60(21), 2976-2994.e13 (2025)

Ohba Y, Fujiwara C, Arita M. Mitochondrial cardiolipin remodeling facilitates efficient myoblast differentiation. J Lipid Res 66(11), 100909 (2025)

Ohtani H, Fujiki Y, Takamura S, Miyazawa M. Identification of proliferating CD103+ CD8+ tissue-resident memory-like T-cells in villitis of unknown etiology in human placenta. Virchows Arch 488(6), 1341-1349 (2025)

Ohtani M, Fujii H, Watanabe T, Ohara O, Maruya M, Fagarasan S, Hoshii T, Hirao A, Koyasu S, Kubo M, Matsuda S. mTORC1-independent IgA production: a unique pathway for gut immune homeostasis. Int Immunol dxaf063 (2025)

Okada M, Tateishi Y, Nojiri E, Mikawa T, Rajesh S, Ogasa H, Ueda T, Yagi H, Kohno T, Kigawa T, Shimada I, Guntert P, Ito Y, Ikeya T. Multistate Structure Determination and Dynamics Analysis Reveals a Unique Ubiquitin-Recognition Mechanism in Ubiquitin C-terminal Hydrolase. J Am Chem Soc (2025)

Okazaki T, Nozaki K, Morimoto N, Otobe Y, Saito R, Abe S, Okajima M, Yoshitane H, Hatta T, Iemura S, Natsume T, Kosako H, Yamasaki M, Inoue S, Kondo T, Koseki H, Gotoh Y. Membrane topology inversion of GGCX mediates cytoplasmic carboxylation for antiviral defense. Science 389(6755), 84-91 (2025)

Onagi H, Son R, Oguchi A, Sano K, Sasa K, Hasegawa N, Akaike K, Kubota D, Takagi T, Hayashi T, Ishijima M, Yao T, Suehara Y, Murakawa Y, Saito T. Potential Involvement of Myostatin in Smooth Muscle Differentiation in Pleomorphic Leiomyosarcoma. Int J Mol Sci 26(16), 7676 (2025)

Ono N, Ito Y, Aoki S, Shiohama A, Sasaki T, Kurokawa R, Suda W, Amagai M, Kubo A. Microbial Dysbiosis and Foot Odor in Nagashima-Type Palmoplantar Keratosis: Improvement with Topical Benzoyl Peroxide. J Invest Dermatol (2025)

Ortega-Reyes D, Takeuchi T, Ogata Y, Iwami T, Suda W, Kubota T, Kubota N, Kadowaki T, Tomizuka K, Ohno H, Horikoshi M, Terao C. Interplay between host genetics and gut microbiome composition in the Japanese population. Front Microbiomes 4, 1635907 (2025)

Ozaki K, Aoki T, Kobayashi M, Takami M, Kobayashi M, Ito T, Ogawa K, Tanaka H, Nishii K, Nishimura K, Motoyoshi K, Kojima I, Katsumi D, Shimizu D, Wang H, Kimura MY, Hirahara K, Koseki H, Higuchi Y, Motohashi S. Anti-tumor effect of intratumoral administration of induced pluripotent stem cell-derived NKT cells on glioblastoma through CD155/DNAM-1 interaction. Stem Cells Transl Med 14(9), szaf036 (2025)

Patrinos GP, Reichardt JK, Carninci P, Hamosh A, Mitropoulou C, Vasiliou V. Bringing our genomes to medicine - the 2026 human genome meeting. Hum Genomics 19(1), 93 (2025)

Qin X, Sakamoto Y, Wei F, Nishimura H, Nakanishi Y, Maeda S, Suzuki H. Physicochemical features of intrinsically disordered regions predict DNA-demethylation-promoting activity of transcription factors. Epigenetics Chromatin 19(1), 1 (2025)

Ramirez P, Sun W, Dehkordi SK, Zare H, Pascarella G, Carninci P, Fongang B, Bieniek KF, Frost B. Long-read sequencing reveals genomic and epigenomic variation in the dark genome of human Alzheimer's disease. Alzheimers Dement 21(11), e70852 (2025)

Roselli C, Surakka I, Olesen MS, Sveinbjornsson G, Marston NA, Choi SH, Holm H, Chaffin M, Gudbjartsson D, Hill MC, Aegisdottir H, Albert CM, Alonso A, Anderson CD, Arking DE, Arnar DO, Barnard J, Benjamin EJ, Braunwald E, Brumpton B, Campbell A, Chami N, Chasman DI, Cho K, Choi EK, Christophersen IE, Chung MK, Conen D, Crijns HJ, Cutler MJ, Czuba T, Damrauer SM, Dichgans M, Dörr M, Dudink E, Duong T, Erikstrup C, Esko T, Fatkin D, Faul JD, Ferreira M, Freitag DF, Ganesh SK, Gaziano JM, Geelhoed B, Ghouse J, Gieger C, Giulianini F, Graham SE, Gudnason V, Guo X, Haggerty C, Hayward C, Heckbert SR, Hveem K, Ito K, Johnson R, Jukema JW, Jurgens SJ, Kääb S, Kane JP, Kany S, Kardia SLR, Kavousi M, Khurshid S, Kamanu FK, Kirchhof P, Kleber ME, Knight S, Komuro I, Krieger JE, Launer LJ, Li D, Lin H, Lin HJ, Loos RJF, Lotta L, Lubitz SA, Lunetta KL, Macfarlane PW, Magnusson PKE, Malik R, Mantineo H, Marcus GM, März W, McManus DD, Melander O, Melloni GEM, Meyre PB, Miyazawa K, Mohanty S, Monfort LM, Müller-Nurasyid M, Nafissi NA, Natale A, Nazarian S, Ostrowski SR, Pak HN, Pang S, Pedersen OB, Pedersen NL, Pereira AC, Pirruccello JP, Preuss M, Psaty BM, Pullinger CR, Rader DJ, Rämö JT, Ridker PM, Rienstra M, Risch L, Roden DM, Rotter JI, Sabatine MS, Schunkert H, Shah SH, Shim J, Shoemaker MB, Simonson B, Sinner MF, Smit RAJ, Smith JA, Smith NL, Smith JG, Soliman EZ, Sørensen E, Sotoodehnia N, Strbian D, Stricker BH, Teder-Laving M, Sun YV, Thériault S, Thorolfsdottir RB, Thorsteinsdottir U, Tveit A, van der Harst P, van Meurs J, Wang B, Weiss S, Wells QS, Weng L-C, Wilson PW, Xiao L, Yang P-S, Yao J, Yoneda ZT, Zeller T, Zeng L, Zhao W, Zhou X, Zöllner S; BioBank Japan Project; Regeneron Genetics Center; DBDS Genomic Consortium; Ruff CT, Bundgaard H, Willer C, Stefansson K, Ellinor PT. Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases. Nat Genet 57(3), 539-547 (2025)

Rowntree LC, Allen LF, Hagen RR, McQuilten HA, Quadeer AA, Chaurasia P, Kaewpreedee P, Lee KW, Cohen CA, Petersen J, Littler DR, Habel JR, Zhang W, Cheng SM, Chan KK, Kwok JS, Leung KS, Wu JT, Lee C, Davies J, Pannaraj PS, Allen EK, Thomas PG, Tosif S, Crawford NW, Lappas M, Thevarajan I, Lewin SR, Kent SJ, Juno JA, Bond KA, Williamson DA, Holmes NE, Smibert OC, Gordon CL, Trubiano JA, Kotsimbos TC, Cheng AC, Efstathiou C, Turtle L, Thwaites RS, Brightling CE, Group PC, Rossjohn J, McKay MR, Tian J, Liu WJ, Gao GF, Xu J, Sonehara K, Ishii KJ, Namkoong H, Okada Y, Peiris M, Hui DS, Poon LL, Doherty PC, Nguyen TH, Valkenburg SA, Kedzierska K. HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes. Proc Natl Acad Sci U S A 122(36), e2503145122 (2025)

Saito Y, Ishikawa M, Ohkuma M, Moody J, Mabuchi Y, Sanosaka T, Ando Y, Yamashita T, Hon C, Shin JW, Akamatsu W, Okano H. NEUROD1 efficiently converts peripheral blood cells into neurons with partial reprogramming by pluripotency factors. Proc Natl Acad Sci U S A 122(18), e2401387122 (2025)

Sakamoto Y, Takahashi M, Nishimura H, Watanabe K, Suzuki H. Regulation of divergent epithelial-to-mesenchymal transition responses via the CDK4/6-USP51 pathway through ZEB1 protein stabilization. Sci Rep 15, 1-12 (2025)

Sakata H, Matsubara H, Gomi K, Miyazaki M. Lipid composition effects on the number and size of liposomes formed by the inverted emulsion method. Biophys J (2025)

Sakurada K, Ishikawa T, Oba J, Kuno M, Okano Y, Sakamaki T, Tamura T. Medical AI and AI for Medical Sciences. JMA Journal 8(1), 26-37 (2025)

Sakurai K, Chubachi S, Miyata J, Hamamoto J, Naganuma T, Shimada T, Otake S, Nakayama S, Irie H, Tsutsumi A, Kameyama N, Hegab AE, Shimoda M, Terai H, Yasuda H, Kanai Y, Arita M, Fukunaga K. Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice. Front Immunol 16, 1557790 (2025)

Sambe T, Imamura C, Fukunaga K, Mushiroda T, Kobayashi S. Lack of effects of S-equol-containing supplement on the pharmacokinetics of oral hormone therapy drugs for breast cancer. Cancer Chemother Pharmacol 95(1), 123 (2025)

Saminathan P, Mathews IT, Alimadadi A, Fung K, Kakugawa K, Joosten LA, Netea MG, Jain M, Cheng S, Hedrick CC, Sharma S. Sex differences in adenosine deaminase activity associate with disparities in SARS-CoV-2 innate immunity. iScience 28(5), 112418 (2025)

Sasa N, Kojima S, Koide R, Hasegawa T, Namkoong H, Hirota T, Watanabe R, Nakamura Y, Oguro-Igashira E, Ogawa K, Yata T, Sonehara K, Yamamoto K, Kishikawa T, Sakaue S, Edahiro R, Shirai Y, Maeda Y, Nii T, Chubachi S, Tanaka H, Yabukami H, Suzuki A, Nakajima K, Arase N, Okamoto T, Nishikawa R, Namba S, Naito T, Miyagawa I, Tanaka H, Ueno M, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Ikumi K, Nishida E, Nakagawa I, Yagita-Sakamaki M, Yoshimura M, Ohshima S, Kinoshita M, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Uchida A, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Saigusa M, Shirai T, Hizawa N, Nakata K, Imafuku S, Tada Y, Asano Y, Sato S, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Kawamura T, Shimada S, Katayama I, Poisner HM, Mack TM, Bick AG, Higasa K, Okuno T, Mochizuki H, Ishii M, Koike R, Kimura A, Noguchi E, Sano S, Inohara H, Fujimoto M, Inoue Y, Yamaguchi E, Ogawa S, Kanai T, Morita A, Matsuda F, Tamari M, Kumanogoh A, Tanaka Y, Ohmura K, Fukunaga K, Imoto S, Miyano S, Parrish NF, Okada Y. Blood DNA virome associates with autoimmune diseases and COVID-19. Nat Genet 57(1), 65-79 (2025)

Sasagawa H, Narita S, Matsuda K, Kosaka T, Momozawa Y. Revisiting the impact of BRCA1 pathogenic variants on the aggressiveness of prostate cancer. JNCI Cancer Spectr (2025)

Sasaki T, Iwaya T, Yaegashi M, Idogawa M, Hiraki H, Abe M, Koizumi Y, Sasaki N, Yashima-Abo A, Fujisawa R, Endo F, Tange S, Otsuka K, Sasaki A, Masuda M, Fujita M, Nakagawa H, Takahashi F, Sasaki Y, Tokino T, Nishizuka SS. Impact of Sensitive Circulating Tumor DNA Monitoring on CT Scan Intervals During Postoperative Colorectal Cancer Surveillance. Ann Surg Open 6(1), e549 (2025)

Sasmal P, Miyazaki M, Carlier-Grynkorn F, Tran PT. Chimeras of kinesin-6 and kinesin-14 reveal head-neck-tail domain functions and dysfunctions that lead to aneuploidy in fission yeast. Curr Biol (2025)

Saumya A, Kanamaru E, Saito Y, Ishikawa F, De Hoon MJ. Cell type-dependent directional transcription at enhancers. NAR Genom Bioinform 7(1), lqaf007 (2025)

Schebb NH, Kampschulte N, Hagn G, Plitzko K, Meckelmann SW, Ghosh S, Joshi R, Kuligowski J, Vuckovic D, Botana MT, Sánchez-Illana Á, Zandkarimi F, Das A, Yang J, Schmidt L, Checa A, Roche HM, Armando AM, Edin ML, Lih FB, Aristizabal-Henao JJ, Miyamoto S, Giuffrida F, Moussaieff A, Domingues R, Rothe M, Hinz C, Das US, Rund KM, Taha AY, Hofstetter RK, Werner M, Werz O, Kahnt AS, Bertrand-Michel J, Le Faouder P, Gurke R, Thomas D, Torta F, Milic I, Dias IH, Spickett CM, Biagini D, Lomonaco T, Idborg H, Liu J, Fedorova M, Ford DA, Barden A, Mori TA, Kennedy PD, Maxey K, Ivanisevic J, Gallart-Ayala H, Gladine C, Wenk M, Galano J, Durand T, Stark KD, Barbas C, Garscha U, Gelhaus SL, Ceglarek U, Flamand N, Griffin JL, Ahrends R, Arita M, Zeldin DC, Schopfer FJ, Quehenberger O, Julian R, Nicolaou A, Blair IA, Murphy MP, Hammock BD, Freeman B, Liebisch G, Serhan CN, Köfeler HC, Jakobsson P, Steinhilber D, Gelb MH, Holčapek M, Andrew R, Giera M, FitzGerald GA, Murphy RC, Newman JW, Dennis EA, Ekroos K, Milne GL, Gijón MA, Vesper HW, Wheelock CE, O'Donnell VB. Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry. Sci Signal 18(887), eadw1245 (2025)

Schiele P, Japp AS, Stark R, Sattelberg JJ, Nikolaou C, Kornhuber G, Abbasi P, Ding N, Rosnev S, Meinke S, Mühle K, Loyal L, Braun J, Dingeldey M, Durlanik S, Matzmohr N, Ponikwicka-Tyszko D, Wolczynski S, Rahman NA, Taniuchi I, Schlickeiser S, Giesecke-Thiel C, Blankenstein T, Na I, Thiel A, Frentsch M. CD8+ T cell-derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells. Sci Adv 11(21), eadr9331 (2025)

Sekiguchi A, Shimokawa C, Kato T, Uchiyama A, Yokoyama Y, Ogino S, Torii R, Hisaeda H, Ohno H, Motegi S. Inhibition of skin fibrosis via regulation of Th17/Treg imbalance in systemic sclerosis. Sci Rep 15(1), 1423 (2025)

Sekine S. Toward structural understanding of eukaryotic transcription elongation. Proc Jpn Acad Ser B Phys Biol Sci 101(7), 414-430 (2025)

Sharma S, Gibbons A, Saphire EO. Sex differences in tissue-specific immunity and immunology. Science 389(6760), 599-603 (2025)

Shikimachi R, Matsuzawa S, Onoda H, Konuma T, Yamagata A, Shirouzu M, Yamaguchi K, Arita K. Structural basis for E3 ubiquitin ligase UHRF1 binding to nucleosome core particle and histone H3 ubiquitination. J Biol Chem 301(12), 110894 (2025)

Shimada T, Tanabe N, Chubachi S, Asakura T, Namkoong H, Tanaka H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Watase M, Maetani T, Shiraishi Y, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Extent of pulmonary involvement on admission predicts long-term pulmonary and muscular sequelae of COVID-19: A longitudinal computed tomography study. Respir Investig 63(6), 1215-1220 (2025)

Shimagami H, Nishimura K, Matsushita H, Metsugi S, Kato Y, Kawasaki T, Tsujimoto K, Edahiro R, Itotagawa E, Naito M, Kawada S, Nakatsubo D, Matsukawa K, Namba-Hamano T, Inoue K, Takahashi A, Mizui M, Kato S, Hikita H, Nakazawa S, Kakuta Y, Konaka H, Mitsumoto K, Ishikawa N, Fujimoto J, Higa S, Omiya R, Isaka Y, Takehara T, Nonomura N, Okada Y, Hattori K, Narazaki M, Kumanogoh A, Nishide M. Single-cell analysis reveals immune cell abnormalities underlying the clinical heterogeneity of patients with systemic sclerosis. Nat Commun 16(1), 4949 (2025)

Shimba A, Cui G, Abe S, Hirota K, Miyauchi E, Takami D, Tani-Ichi S, Kato R, Tajima M, Kanahashi T, Miyazaki M, Rodewald H, Yoshitomi H, Ueno H, Ohno H, Ikuta K. Stress-induced glucocorticoids enhance acute inflammation by promoting the differentiation of Th17 cells. Cell Rep 44(8), 116093 (2025)

Shimizu K, Sanpei A, Nakazato H, Shinga J, Ueda S, Liu Y, Iyoda T, Yamasaki S, Nakabayashi J, Fujii S. Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity. Cell Rep 44(6), 115800 (2025)

Shinoda T, Katsura K, Ishizuka-Katsura Y, Hanada K, Yonemochi M, Miyamoto Y, Kukimoto-Niino M, Yamauchi J, Shirouzu M. Conformational alteration of DOCK5•ELMO1 signalosome on lipid membrane. Commun Biol 8(1), 1523 (2025)

Shirai Y, Enomoto T, Takeda Y, Edahiro R, Takahashi-Itoh M, Noda Y, Adachi Y, Nakayama M, Kawasaki T, Koba T, Futami Y, Yoshimura H, Amiya S, Hara R, Yamamoto M, Nakatsubo D, Suga Y, Naito M, Masuhiro K, Matsuki T, Hirata H, Iwahori K, Nagatomo I, Miyake K, Koyama S, Fukushima K, Shiroyama T, Naito Y, Futami S, Natsume-Kitatani Y, Ose N, Funaki S, Nojima S, Shichino S, Yanagawa M, Shintani Y, Nogami-Itoh M, Adachi J, Inoue Y, Tomonaga T, Okada Y, Mizuguchi K, Kumanogoh A. Serum vesicle biomarkers reflect the disease activity of idiopathic pulmonary fibrosis. J Transl Med 23(1), 1102 (2025)

Shitanda I, Chiba M, Noya L, Yoshizawa H, Motosuke M, Mukaimoto T, Yanagita S, Suzuki T, Mikawa T, Watanabe H, Itagaki M. Wearable Microfluidic Dual Screen-Printed Sensor for Simultaneous Monitoring of Sweat pH and Lactate. Electrochemistry 93(11), 117001 (2025)

Shitanda I, Samori T, Satake M, Loew N, Motosuke M, Mukaimoto T, Yanagita S, Suzuki T, Mikawa T, Tsujimura S, Watanabe H, Itagaki M. Wearable Self-Powered Biosensor for Continuous Lactate Monitoring in Sweat. ChemElectroChem 12(20), e202500222 (2025)

Small AM, Yang TY, Itoh S, Thériault S, Dufresne L, Kurosawa R, Komuro I, Matsuda K, Vy HMT, Farber-Eger EH, Shaffer LL, Boulier KM, Corey KM, Ramaker ME, Laporte F, Schott JJ, Le Scouarnec S, Singh SA, Sonawane AR, Smith HA, Rafaels N; Colorado Center for Personalized Medicine; Ghouse J, Raja AA, Ostrowski SR, Sørensen E, Mikkelsen C, Pedersen OB, Erikstrup C, Ullum H; DBDS Genomic Consortium; Sveinbjornsson G, Gudbjartsson DF, Abner E; Estonian Biobank Research Team; Lee J, Ganna A, Nowak-Göttl U, Finer S; Genes & Health Research Team; Schumacher J, Maj C, Al-Kassou B, Nickenig G, Trenkwalder T, Dreβen M, Krane M, Nöthen MM, Moksnes MR, Brumpton BM, Knight S, Knowlton KU, Nadauld L, Debiec R, Musameh MD, Braund PS, Nelson CP, Czuba T, Melander O, Selvaraj MS, Koyama S, Bhukar R, Ruan Y, Ljungberg J, Damrauer SM, Levin MG, Franke A, Berger K, Ruff CT, Melloni GEM, Kamanu FK, Ito K, Do R, Loos RJF, Schunkert H, Wells QS, Shah SH, Le Tourneau T, Messika-Zeitoun D, Gignoux C, Bundgaard H, Larsson SC, Michaëlsson K, Holm H, Helgadottir A, Esko T, van Heel DA, Mathieu P, Samani NJ, Smith JG, Söderberg S, Rader DJ, Marston NA, Sabatine MS, Pasaniuc B, Cho K, Wilson PWF, O'Donnell CJ, Stefansson K, Bossé Y, Aikawa E, Engert JC, Peloso GM, Natarajan P, Thanassoulis G. Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction. Nat Genet (2025)

Smit RA, Wade KH, Hui Q, Arias JD, Yin X, Christiansen MR, Yengo L, Preuss MH, Nakabuye M, Rocheleau G, Graham SE, Buchanan VL, Chittoor G, Graff M, Guindo-Martinez M, Lu Y, Marouli E, Sakaue S, Spracklen CN, Vedantam S, Wilson EP, Chen S, Ferreira T, Ji Y, Karaderi T, Luell K, Machado M, Malden DE, Medina-Gomez C, Moore A, Rueeger S, Akiyama M, Allison MA, Alvarez M, Andersen MK, Appadurai V, Arbeeva L, Bartell E, Bhaskar S, Bielak LF, Bis JC, Bollepalli S, Bork-Jensen J, Bradfield JP, Bradford Y, Brandl C, Braund PS, Brody JA, Broeckel U, Burgdorf KS, Cade BE, Cai Q, Camarda S, Campbell A, Canadas-Garre M, Chai J, Chesi A, Choi SH, Christofidou P, Couture C, Cuellar-Partida G, Danning R, Degenhardt F, Delgado GE, Delitala A, Demirkan A, Deng X, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Eichelmann F, Eliasen AU, Engmann JE, Erdos MR, Fairhurst-Hunter Z, Farmaki A, Faul JD, Fernandez-Lopez J, Forer L, Frank M, Freitag-Wolf S, Fritsche LG, Fuchsberger C, Galesloot TE, Gao Y, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, Heard-Costa N, Hemerich D, Highland HM, Hindy G, Ho Y, Hofer E, Holliday E, Horn K, Hornsby WE, Hottenga J, Huang H, Huang J, Huerta-Chagoya A, Huo S, Hwang MY, Hwu C, Iha H, Ikeda DD, Isono M, Jackson AU, Jansen IE, Jiang Y, Johansson I, Jonsson A, Jorgensen T, Kalafati IP, Kanai M, Kanoni S, Karhus LL, Kasturiratne A, Katsuya T, Kawaguchi T, Kember RL, Kentistou KA, Kim D, Kim H, Kim YJ, Kleber ME, Knol MJ, Kurbasic A, Lauzon M, Le P, Lea R, Lee J, Lee W, Leonard HL, Li H, Li SA, Li X, Li X, Liang J, Lin H, Lin K, Liu J, Liu X, Lo KS, Long J, Lores-Motta L, Luan J, Lyssenko V, Lyytikaeinen L, Mahajan A, Malik MZ, Mamakou V, Mangino M, Manichaikul A, Marten J, Mattheisen M, McDaid AF, Mei Q, Meiselbach H, Melendez TL, Milaneschi Y, Miller JE, Millwood IY, Mishra PP, Mitchell RE, Mollehave LT, Mononen N, Mucha S, Munz M, Mykkaenen J, Nakatochi M, Nardone GG, Nelson CP, Nethander M, Nho CW, Nielsen AA, Nolte IM, Nongmaithem SS, Noordam R, Ntalla I, Nutile T, Pandit A, Pauper M, Petersen ER, Petersen LV, Piluso F, Polasek O, Poveda A, Pyarajan S, Raffield LM, Rakugi H, Ramirez J, Rasheed A, Raven D, Rayner NW, Riveros C, Rohde R, Ruggiero D, Ruotsalainen SE, Ryan KA, Sabater-Lleal M, Santin A, Saxena R, Scholz M, Shen B, Shi J, Shin JH, Sidore C, Sidorenko J, Sim X, Slieker RC, Smith AV, Smith JA, Smyth LJ, Southam L, Steinthorsdottir V, Sun L, Takeuchi F, Taylor KD, Tayo BO, Tcheandjieu C, Terzikhan N, Tesolin P, Teumer A, Theusch E, Thompson DJ, Thorleifsson G, Timmers PR, Trompet S, Turman C, Vaccargiu S, van der Laan SW, van der Most PJ, van Klinken JB, van Setten J, Verma SS, Verweij N, Veturi Y, Wang CA, Wang C, Wang J, Wang L, Wang YX, Wang Z, Warren HR, Wei WB, Wen W, Wheeler WA, Wickremasinghe AR, Wielscher M, Winsvold BS, Wong A, Wuttke M, Xia R, Yamamoto K, Yang J, Yao J, Young H, Yousri NA, Yu L, Zeng L, Zhang W, Zhang X, Zhao J, Zhao W, Zhou W, Zimmermann ME, Zoledziewska M, 't Hart LM, Adair LS, Adams HH, Aguilar-Salinas CA, Al-Mulla F, Arnett DK, Asselbergs FW, Asvold BO, Attia J, Banas B, Bandinelli S, Beilin LJ, Bennett DA, Bergler T, Bharadwaj D, Biino G, Boerwinkle E, Boeger CA, Borja JB, Bouchard C, Bowden DW, Brandslund I, Ben Brumpton, Buring JE, Caulfield MJ, Chambers JC, Chandak GR, Chanock SJ, Chaturvedi N, Chen YI, Chen Z, Cheng C, Cho YS, Christensen K, Christophersen IE, Ciullo M, Cole JW, Collins FS, Concas MP, Cooper RS, Cruz M, Cucca F, Cutler MJ, Damrauer SM, Dantoft TM, de Borst GJ, de Geus EJ, de Groot LC, De Jager PL, de Kleijn DP, de Silva HJ, Dedoussis GV, den Hollander AI, Du S, Easton DF, Eckardt K, Elders PJ, Eliassen AH, Ellinor PT, Elmstahl S, Erdmann J, Evans MK, Fatkin D, Feenstra B, Feitosa MF, Ferrucci L, Florez JC, Ford I, Fornage M, Franke A, Franks PW, Freedman BI, Gieger C, Girotto G, Golightly YM, Gonzalez-Villalpando C, Gordon-Larsen P, Grallert H, Grant SF, Grarup N, Griffiths L, Gudnason V, Haiman C, Hakonarson H, Hansen T, Hartman CA, Hattersley AT, Hayward C, Heid IM, Heng C, Hengstenberg C, Herzig K, Hewitt AW, Hishigaki H, Hougaard DM, Hoyng CB, Huang PL, Huang W, Huang W, Huffman JE, Hunt SC, Hutri N, Hveem K, Hyppoenen E, Iacono WG, Ichihara S, Ikram MA, Isasi CR, Jarvelin M, Jin Z, Joeckel K, Jonas JB, Joshi PK, Jousilahti P, Jukema JW, Kaehoenen M, Kamatani Y, Kang KD, Kaprio J, Kardia SL, Karpe F, Kato N, Kavousi M, Kee F, Kessler T, Khera AV, Khor CC, Kiemeney LA, Kim B, Kim EK, Kim H, Kirchhof P, Kivimaki M, Koh W, Koistinen HA, Kokkinos A, Kooner JS, Kooperberg C, Kovacs P, Kraaijeveld A, Kraft P, Krauss RM, Kumari M, Kutalik Z, Laakso M, Lange LA, Langenberg C, Launer LJ, Lee H, Lee NR, Lehtimaeki T, Lemaitre RN, Li H, Li L, Lieb W, Lin X, Lind L, Linneberg A, Liu C, Liu J, Loeffler M, London B, Lu F, Lubitz SA, Mackey DA, Magnusson PK, Manson JE, Marcus GM, Marques Vidal P, Martin NG, Maerz W, Matsuda F, McCarthy MI, McGarrah RW, McGue M, McKnight AJ, Medland SE, Mellstroem D, Metspalu A, Mitchell BD, Mitchell P, Mook-Kanamori DO, Mori TA, Morris AD, Mucci LA, Munroe PB, Nalls MA, Nazarian S, Nelson AE, Neville MJ, Newton-Cheh C, Nielsen CS, Niinikoski H, Nikus K, Noethen MM, Ogunniyi A, Ohlsson C, Oldehinkel AJ, Orozco L, Pahkala K, Pajukanta P, Palmer CN, Parra EJ, Pattaro C, Pedersen O, Pennell CE, Penninx BW, Perusse L, Peters A, Peyser PA, Porteous DJ, Posthuma D, Power C, Pramstaller PP, Province MA, Psaty BM, Qi Q, Qu J, Rader DJ, Raitakari OT, Rallidis LS, Rao DC, Redline S, Reilly DF, Reiner AP, Rhee SY, Ridker PM, Rienstra M, Ripatti S, Ritchie MD, Rivadeneira F, Roden DM, Rosendaal FR, Rotter JI, Rudan I, Rutters F, Ryu S, Sabanayagam C, Salako B, Saleheen D, Salomaa V, Samani NJ, Sanghera DK, Sattar N, Schmidt B, Schmidt H, Schmidt R, Schulze MB, Schunkert H, Scott LJ, Scott RJ, Sever P, Sheu WH, Shoemaker MB, Shu X, Simonsick EM, Sims M, Singleton AB, Sinner MF, Smith JG, Snieder H, Spector TD, Spedicati B, Stampfer MJ, Stark KJ, Strachan DP, Tabara Y, Tai ES, Tang H, Tardif J, Thanaraj TA, Toenjes A, Tuomi T, Tuomilehto J, Tusie-Luna M, van Dam RM, van der Harst P, van der Velde N, van Duijn CM, van Schoor NM, Vitart V, Vohl M, Voelker U, Vollenweider P, Voelzke H, Vrieze S, Wacher-Rodarte NH, Walker M, Wander GS, Wareham NJ, Watanabe RM, Watkins H, Weir DR, Werge TM, Widen E, Willemsen G, Willett WC, Wilson JF, Wilson PW, Wong TY, Woo J, Wright AF, Xu H, Yajnik CS, Yang J, Yokota M, Yuan J, Zeggini E, Zemel BS, Zheng W, Zhu X, Zillikens MC, Zonderman AB, Zwart J, Abecasis GR, Assimes TL, Auton A, Boehnke M, Chasman DI, Esko T, Stefansson K, Lettre G, Lindgren CM, Ng MC, O'Donnell CJ, Thorsteinsdottir U, Visscher PM, Walters RG, Winkler TW, Wood AR, Deloukas P, Frayling TM, Justice AE, Kilpelainen TO, Locke AE, Mohlke KL, North KE, Okada Y, Willer CJ, Young KL, Fatumo S, McCaffery JM, Timpson NJ, Hirschhorn JN, Sun YV, Berndt SI, Loos RJF. Polygenic prediction of body mass index and obesity through the life course and across ancestries. Nat Med 31(9), 3151-3168 (2025)

Sonehara K, Watanabe R, Matsumura Y, Mitsui Y, Ogawa Y, Odomari K, Sakaue S, Namba S, Komuro M, Edamoto M, Watanabe J, Hirota T, Arase N, Nakamura Y, Nakajima K, Okamoto T, Nishikawa R, Yamamoto K, Suzuki K, Kishikawa T, Edahiro R, Shirai Y, Naito T, Sasa N, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Miyagawa I, Tanaka H, Ueno M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Nishida E, Project BJ, Matsuda K, Shojima N, Nakagawa I, Asano Y, Sato S, Imafuku S, Tada Y, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Yamauchi T, Kadowaki T, Kawamura T, Shimada S, Katayama I, Higasa K, Noguchi E, Sano S, Tanaka Y, Matsuda F, Kumanogoh A, Tamari M, Satoh T, Fujimoto M, Morita A, Okada Y. Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene. Cell Genomics 5(10), 100978 (2025)

Song M, Shao Z, Han Y, Zhao Y, Lv J, Yu C, Pei P, Yang L, Millwood IY, Walters RG, Chen Y, Du H, Yang X, Wang M, Chen J, Chen Z, Genovese G, Terao C, Li L, Sun D. Expanded mosaic chromosomal alterations, frailty, and risks of all-cause and cause-specific mortality among Chinese and the UK adults: evidence from two prospective cohorts. BMC Med 23(1), 629 (2025)

Sugawara I, Kawahara Y, Takayasu L, Isshi K, Kato M, Ono S, Hara Y, Futakuchi T, Furuhashi H, Kurokawa R, Sumiyama K, Suda W. Study on the relationship between microbial composition within obstructive biliary stents and the severity of obstruction and duration of stent placement. PLoS One 20(1), e0317230 (2025)

Sugino Y, Bao X, Sekito S, Miyachi S, Kageyama T, Sasaki T, Nishikawa K, Tanaka T, Kato M, Shimada Y, Takano K, Son R, Zang L, Nakayama K, Watanabe M, Murakawa Y, Inoue T. Zebrafish Xenograft Model for Predicting Cisplatin Efficacy in Muscle-Invasive Bladder Cancer. Cancer Sci 116(12), 3376-3387 (2025)

Sukigara Y, Kamoshida H, Tokunaga Y, Fujisaki M, Imai M, Kobayoashi Y, Kofuku Y, Ueda T, Shimada I, Takeuchi K. Cell Permeability and Target Engagement of Middle-Sized Molecules Quantified by In-Cell NMR. Anal Chem 97(35), 18955-18964 (2025)

Tahara U, Amagai M. Keratinocyte-neutrophil interactions revealed as targetable drivers of sustained inflammation in Sweet syndrome. J Clin Invest 135(20), e198494 (2025)

Takahashi H, Fukuda K, Ito Y, Amagai M. Antigen-specific immune responses and microbiota interactions in skin: Insights into autoimmune skin diseases and emerging therapeutic strategies. J Allergy Clin Immunol 156(3), 557-567 (2025)

Takahashi Y, Wang QS, Hasegawa T, Namkoong H, Inoue F, Fukunaga K, Imoto S, Miyano S, Okada Y. JOB: Japan Omics Browser provides integrative visualization of multi-omics data. BMC Genomics 26(1), 451 (2025)

Takao T, Matsui A, Kikutake C, Kan-o K, Inoue A, Suyama M, Okamoto I, Ito M. Maternal asthma imprints fetal lung ILC2s via glucocorticoid signaling leading to worsened allergic airway inflammation in murine adult offspring. Nat Commun 16(1), 631 (2025)

Takehara T, Nakanishi M, Son R, Suemori H, Murakawa Y, Teramura T. Acetylation of lysine 49 on Ctnnb1 drives naïve pluripotency in murine stem cells by modulating Nanog function. PNAS Nexus 4(10), pgaf297 (2025)

Takehara Y, Usui Y, Stolařová L, Kleiblova P, Iwasaki Y, Johnson TA, Hirata M, Kamatani Y, Murakami Y, Endo M, Shiraishi K, Kohno T, Sugano K, Matsuda K, Yoshida T, Spurdle AB, Nakagawa H, Macurek L, Kleibl Z, Momozawa Y. Case-Control Study for 23 Cancer Types With Functional Analysis of CHEK2: Risk Estimation and Clinical Recommendations in East Asia. JCO Precis Oncol 9(9), e2400945 (2025)

Takeichi H, Suzuki W, Yamashita W, Hiyama A. Perception of nonrigid structures from motion using tracking image gradient vectors. Front Psychol 16(1586648), 1-10 (2025)

Takekoshi Y, Ando H, Kohno T, Takase H, Taguchi T, Arita M, Kobayashi T, Hattori M. Reelin Increases the Sphingomyelin Content of the Plasma Membrane and Affects the Surface Expression of GPI-Anchored Proteins in Hippocampal Neurons. J Neurochem 169(9), e70225 (2025)

Takemori N, Kaulich PT, Hahn J, Schlüter H, Sugiyama N, Tsumagari K, Ishihama Y, Fuchs S, Iwasaki M, Müller F J, Neusüß C, Jeong K, Kohlbacher O, Shimizu Y, Otsuka Y, Sato H, Sasaki K, Minegishi Y, Kodera Y, Fernandez F C, Krichel B, Araki N, Tholey A. Meeting Report: The Japanese-German Symposium on the "Advancement and Application of Proteoform-Centric Proteomics" (Kyoto, Japan, 2024). Proteomics 25(19), 6-10 (2025)

Takeuchi K, Ueda T, Imai M, Fujisaki M, Tsujimura M, Tokunaga Y, Kofuku Y, Shimada I. Two-step target recognition for the competitive inhibition activity of an anti-VEGF aptamer. RNA 31(10), 1368-1378 (2025)

Takeuchi T, Miyauchi E, Nakanishi Y, Ito Y, Kato T, Yaguchi K, Kawasumi M, Tachibana N, Ito A, Shimamoto S, Matsuyama A, Sasaki N, Kimura I, Ohno H. Acetylated cellulose suppresses body mass gain through gut commensals consuming host-accessible carbohydrates. Cell Metab 37(8), 1682-1697, e6 (2025)

Tamura T, Nagai S, Masuda K, Imaeda K, Sugihara E, Yamasaki J, Kawaida M, Otsuki Y, Suina K, Nobusue H, Akahane T, Chiyoda T, Kisu I, Kobayashi Y, Banno K, Sakurada K, Okita H, Yamaguchi R, Ahmed AA, Yamagami W, Saya H, Aoki D, Nagano O. mTOR-mediated p62/SQSTM1 stabilization confers a robust survival mechanism for ovarian cancer. Cancer Lett 616, 217565 (2025)

Tanaka R, Murakami Y, Ellis D, Seita J, Yinga W, Kakuta S, Kumano K, Fukui R, Miyake K. TLR7 responses in glomerular macrophages accelerate the progression of glomerulonephritis in NZBWF1 mice. Int Immunol 37(6), 339-353 (2025)

Tol MJ, Shimanaka Y, Bedard A H, Sapia J, Cui L, Colaço-Gaspar M, Hofer P, Ferrari A, Qian K, Kennelly JP, Lee SD, Gao Y, Xiao X, Gao J, Mack JJ, Weston TA, Williams KJ, Su B, Pan C, Lusis AJ, Pike DP, Reed A, Milosevich N, Cravatt BF, Arita M, Young SG, Ford DA, Zechner R, Vanni S, Tontonoz P. Dietary control of peripheral adipose storage capacity through membrane lipid remodelling. Nat Metab 7(7), 1424-1442 (2025)

Tonouchi K, Yeh C, Cain DW, Moseman EA, Haynes BF, Wagh K, Wiehe K, Kurosaki T, Kelsoe G. On the carrying capacity of the bone marrow survival niche in mice. Front Immunol 16, 1706810 (2025)

Toyama Y, Takeuchi K, Shimada I. Revisiting fluorine relaxation: a perspective on fluorine NMR in structural and dynamic studies of biomolecules. J Magn Reson 383, 108006 (2025)

Uchiyama S, Ishikawa Y, Ikari K, Honda S, Hikino K, Tanaka E, Kamatani Y, Gono T, Genovese G, Kuwana M, Terao C. Mosaic loss of chromosome Y characterises late-onset rheumatoid arthritis and contrasting associations of polygenic risk score based on age at onset. Ann Rheum Dis 84(8), 1313-1323 (2025)

Ueda T, Tsuchida T, Kurita M, Mizumura T, Imai S, Shiraishi Y, Kofuku Y, Miyakawa S, Fukuzawa K, Takeuchi K, Shimada I. Structural basis of the residence time of adenosine A2A receptor ligands revealed by NMR. Chem Sci 16(38), 17948-17955 (2025)

Uno Y, Fukunaga K, Mizukami K, Aoi T, Mushiroda T, Momozawa Y, Yamazaki H. Genetic variants in dog cytochrome P450 2B6 and their relevance to interindividual variability of oxidations of probe drug propofol. Drug Metab Dispos 53(12), 100189 (2025)

Uno Y, Fukunaga K, Ushirozako G, Murayama N, Mizukami K, Aoi T, Tomiyasu H, Honnami M, Tsujimoto H, Sakaguchi M, Hisasue M, Mushiroda T, Momozawa Y, Yamazaki H. Genetic variants of cytochrome P450 2C21 identified by screening 6344 dogs influenced oxidations of the probe drug omeprazole. Biochem Pharmacol 242(Pt 4), 117394 (2025)

Unohara T, Fujii R, Watanabe T, Matsuura A, Torii Y, Kita K, Ishizu M, Hara M, Nishida Y, Nagayoshi M, Matsunaga T, Okada R, Kubo Y, Tanoue S, Hidaka Y, Nishiyama T, Nakagawa-Senda H, Koyama T, Watanabe I, Kuriki K, Takashima N, Kondo K, Nakatochi M, Momozawa Y, Tamura T, Matsuo K. Coffee intake, genetic variants, and chronic kidney disease: a cross-sectional analysis of the Japan Multi-Institutional Collaborative Cohort (J-MICC) study. Eur J Nutr 64(7), 301 (2025)

Usui Y, Endo M, Iwasaki Y, Iijima H, Nakagawa H, Matsuda K, Momozawa Y. Clinical Significance of TP53-Mutant Clonal Hematopoiesis Across Diseases. Blood Cancer Discov 6(4), 298-306 (2025)

Valdés-Mas R, Leshem A, Zheng D, Cohen Y, Kern L, Zmora N, He Y, Katina C, Eliyahu-Miller S, Yosef-Hevroni T, Richman L, Raykhel B, Allswang S, Better R, Shmueli M, Saftien A, Cullin N, Slamovitz F, Ciocan D, Ouyang KS, Mor U, Dori-Bachash M, Molina S, Levin Y, Atarashi K, Jona G, Puschhof J, Harmelin A, Stettner N, Chen M, Suez J, Honda K, Lieb W, Bang C, Kori M, Maharshak N, Merbl Y, Shibolet O, Halpern Z, Shouval DS, Shamir R, Franke A, Abdeen SK, Shapiro H, Savidor A, Elinav E. Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease. Cell 188(4), 1062-1083. e36 (2025)

van Amerongen RA, Tuit S, Remst DF, Wouters AK, Siekman SL, Hagedoorn RS, van der Steen DM, Kester MG, de Ru AH, van der Horst G, Matsuda M, Ishikawa F, van Veelen PA, Falkenburg JH, Heemskerk MH. TCR-Based Therapy Directed against Kallikrein-Related Peptidase 4 Is Safe and Effective against Prostate Cancer. Cancer Immunol Res 13(8), 1145-1159 (2025)

Wada K, Suda W, Ueno T, Masuoka H, Yamakawa M, Nakashima Y, Sugino M, Mori T, Uchiyama S, Sumoto Y, Kiguchi Y, Hattori M, Nagata C. Gut microbiota associated with equol production in school-age children. Eur J Nutr 64(4), 174 (2025)

Wagner M, Nishikawa H, Koyasu S. Reinventing type 2 immunity in cancer. Nature 637(8045), 296-303 (2025)

Wang J, Zheng A, Liu N, Tan Z, Shi Y, Ma T, Luo S, Zhu L, Zhou Z, Yuan F, Li T, Gong Y, Fang J, Liu L, Zhang X, Bae S, Terao C, Chen Z, Li X, Wang G, Qu K, Guo C. Integrative spatial multiomics analysis reveals regulatory mechanisms of VCAM1+ proximal tubule cells in lupus nephritis. Ann Rheum Dis 84(12), 2021-2033 (2025)

Wang L, He D, Satoh-Takayama N, Zheng C, Xing J. Regulation of antiviral and antimicrobial innate immunity and immune evasion. Cell Mol Life Sci 82(1), 326 (2025)

Wang L, Yang X, Zhao S, Zheng P, Wen W, Xu K, Cheng X, Li Q, Khanshour AM, Koike Y, Liu J, Fan X, Otomo N, Chen Z, Li Y, Li L, Xie H, Zhu P, Li X, Niu Y, Wang S, Liu S, Yuan S, Terao C, Li Z, Chen S, Zhao X, Liu P, Posey JE, Wu Z, Qiu G, group Ds, Ikegawa S, Lupski JR, Rios JJ, Wise CA, Zhang JT, Zhao C, Wu N. EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis. Elife 13, rp95324 (2025)

Watanabe C, Kamisaka K, Takaya D, Kato K, Tsuda K, Shu K, Murayama D, Isobe T, Ohyama T, Kato A, Fukuzawa K, Honma T. Developments and Activities in FMODB up to 2025: A Release Note. Chem-Bio Inform J 25, 130-139 (2025)

Watase M, Shiraishi Y, Chubachi S, Tanabe N, Maetani T, Asakura T, Namkoong H, Tanaka H, Shimada T, Azekawa S, Otake S, Fukushima T, Nakagawara K, Masaki K, Terai H, Mochimaru T, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Okada Y, Koike R, Ishii M, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Coronary Artery Calcification on Chest Computed Tomography as a Predictor of Cardiovascular Adverse Events in Patients With COVID-19 - A Multicenter Retrospective Study in Japan. Circ J 89(3), 373-381 (2025)

Winter TD, Jahagirdar O, Hikino K, Terao C. Using Mendelian randomization to investigate etiologic heterogeneity across renal cell carcinoma subtypes. Int J Epidemiol 54(6), dyaf177 (2025)

Wolford BN, Zhao QY, Wu KH, Yu X, Richter CE, Bhatta L, Brumpton BM, Desch KC, Thibord F, Klarin D, Johnson AD, Trégouët DA, Damrauer SM, Smith NL, INVENT M, Faro VL, Tsuo K, Daly MJ, Neale BM, Zhou W, Willer CJ, Shavit JA, Surakka I. Multipopulation GWAS for venous thromboembolism identifies novel loci followed by experimental validation in zebrafish. Blood Adv 9(19), 4850-4859 (2025)

Wong W, Herzog R, Andrade KC, Andrillon T, de Araujo DB, Arnulf I, Ataei S, Avvenuti G, Baird B, Bellesi M, Bergamo D, Bernardi G, Blagrove M, Decat N, Demirel Ç, Dresler M, Eichenlaub J, Elce V, Gais S, De Gennaro L, Gott J, Hiramatsu C, Juel BE, Konkoly KR, Kumral D, Lacaux C, LaRocque JJ, Lenggenhager B, Mallett R, Mota-Rolim SA, Motomura Y, Nilsen AS, Noreika V, Oudiette D, Palhano-Fontes F, Palmieri J, Paller KA, Perogamvros L, Revonsuo A, van Rijn E, Scarpelli S, Schönauer M, Schoch SF, Siclari F, Sikka P, Storm JF, Takeichi H, Valli K, Wamsley EJ, Windt JM, Zhang J, Zhao J, Tsuchiya N. A dream EEG and mentation database. Nat Commun 16(1), 7495 (2025)

Xu Y, Mishra H, Furutani Y, Yanaka K, Nishimura H, Furuhata E, Takahashi M, Gailhouste L, Suenaga Y, Hippo Y, Yu W, Matsuura T, Suzuki H, Qin X. A high-throughput screening platform to identify MYCN expression inhibitors for liver cancer therapy. Front Oncol 15, 1486671 (2025)

Yagi Y, Kimura T, Watanabe C, Okiyama Y, Tanaka S, Honma T, Kaoru F. Comprehensive Protein-Ligand Interaction Analysis: Fragment Molecular Orbital Calculation on the Complexes of Human Protease Renin and its Inhibitors. Chem-Bio Inform J 25, 107-129 (2025)

Yamada Y, Sadahiro T, Nakano K, Honda S, Abe Y, Akiyama T, Fujita R, Nakamura M, Maeda T, Kuze Y, Onishi M, Seki M, Suzuki Y, Takeuchi C, Iwasaki YW, Murano K, Sakata-Yanagimoto M, Chiba S, Kato H, Sakamoto H, Hiramatsu Y, Ieda M. Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction. Circulation 151(6), 379-395 (2025)

Yamaguchi H, González-Duarte RJ, Qin X, Abe Y, Takada I, Charroy B, Cázares-Ordoñez V, Uno S, Makishima M, Esumi M. Transglutaminase 2 Stimulates Cell Proliferation and Modulates Transforming Growth Factor-Beta Signaling Pathway Independently of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells. Int J Mol Sci 26(12), 5497 (2025)

Yamaguchi M, Nakagawa R, Tran LT, Shimizu Y, Miyazaki M. Kinetic scheme of myosin phosphorylation by ZIP kinase. Biochemistry 64(24), 4805-4817 (2025)

Yamamoto K, Miyazaki M. Optogenetic actin network assembly on lipid bilayer uncovers the network density-dependent functions of actin-binding proteins. Nat Commun 16(1), 7583 (2025)

Yamamoto K. How to analyze and understand the human immune system. Semin Arthritis Rheum 72S, 152696 (2025)

Yamamoto S, Koyanagi YN, Iwashita Y, Shinozaki T, Fujiwara Y, Sakakura N, Hara M, Nishida Y, Otonari J, Ikezaki H, Tanoue S, Koriyama C, Kasugai Y, Oze I, Koyama T, Tomida S, Michihata N, Nakamura Y, Suzuki S, Nakagawa-Senda H, Nagayoshi M, Kubo Y, Kato Y, Wakai K, Watanabe T, Ishizu M, Takashima N, Kadota A, Momozawa Y, Nakatochi M, Tamura T, Niimi A, Ito H, Matsuo K. Smoking behavior-related genetic variants and lung cancer risk in Japanese: an assessment by mediation analysis. Carcinogenesis 46(2), bgaf011 (2025)

Yamamoto Y, Shirai Y, Sonehara K, Namba S, Ojima T, Yamamoto K, Edahiro R, Suzuki K, Kanai A, Oda Y, Suzuki Y, Morisaki T, Narita A, Takeda Y, Tamiya G, Yamamoto M, Matsuda K, Kumanogoh A, Yamauchi T, Kadowaki T, Okada Y. Dissecting cross-population polygenic heterogeneity across respiratory and cardiometabolic diseases. Nat Commun 16(1), 3765 (2025)

Yamane T, Masaoka T, Ishii C, Masuoka H, Suda W, Kurokawa S, Kishimoto T, Mikami Y, Fukuda S, Kanai T. Factors contributing to the efficacy of fecal microbiota transplantation for diarrhea-dominant functional bowel disorders. Digestion 106(5), 469-479(2025)

Yamano H, Horike H, Taguchi Y, Inabu Y, Miyamoto H, Kurotani A, Suzuki N, Moriya S, Nakaguma T, Ishii C, Matsuura M, Tsuji N, Etoh T, Shiotsuka Y, Fujino R, Wada S, Kikuchi J, Ohno H, Takahashi H. Maternal administration of octanoate, a medium-chain fatty acid, improves feed efficiency of Japanese black calves through influencing gut bacteriome structure. Sci Rep 15(1), 33557 (2025)

Yamashita M, An Y, Bhattarai D, Eng-Binas VW, Homvises S, Ismail IH, Jamee M, Jeong DC, McNaughton P, Muktiarti D, Okada S, Van Quang V, Rawat A, Sarmin M, de Silva R, Tenzin P, Try L, Zhong Y, Yu H, Wong JC, Kim Y, Duque JS, Lau YL, Kanegane H. Healthcare resources for inborn errors of immunity in the Asia-Pacific region. J Hum Immun 1(2), e20250023 (2025)

Yamashita M, Kamiya T, Kanegane H. Hematopoietic cell transplantation for leukocyte adhesion deficiency: prevention of graft-versus-host-disease. Expert Rev Hematol 18(11), 883-891 (2025)

Yamashita M, Morio T. IKZF-associated inborn errors of immunity. J Hum Immun 1(3), e20250063 (2025)

Yan Y, Satoh-Takayama N. New perspectives on gastric disorders: the relationship between innate lymphoid cells and microbes in the stomach. Cell Mol Life Sci 82(1), 113 (2025)

Yang J, Pan H, Sekimata K, Hwang C, Kulkarni A, Thomas H, Lindenau J, Duford T, Ueharu H, Tanaka A, Sakai N, Shirouzu M, Hashizume Y, Levi B, Koyama H, Mishina Y. A new BMP type 1 receptor kinase inhibitor for safe and efficient oral treatment to prevent genetically induced heterotopic ossification in mice. Bone 199, 117565 (2025)

Yazaki S, Hori M, Aiba H, Momozawa Y, Yoshida M, Shiino S, Harano K, Yamauchi C, Yamanaka T, Miwa M, Matsuda K, Kawai Y, Kobayashi-Kato M, Kitagawa M, Saito M, Nakagomi H, Tachibana K, Sakamoto I, Takahashi K, Asami Y, Katanoda K, Kuchiba A, Yoshida H, Ishikawa M, Shimoi T, Sudo K, Shimizu C, Shimomura A, Murata T, Yamashita Y, Kogawa T, Fujiwara S, Saji H, Kato H, Miyagi E, Iwasaki Y, Aoi T, Takata S, Ogasawara A, Ohtake T, Fujimori K, Hirotsu Y, Nagashima M, Komatsu M, Hamamoto R, Hirata M, Yoshida T, Honda T, Hiranuma K, Matsuda M, Shimada Y, Sunami K, Noiri E, Omae Y, Matsumoto K, Okamoto A, Omata M, Watanabe T, Miyagi Y, Murakami Y, Tokunaga K, Hasegawa K, Kato T, Onishi T, Yamashita T, Naito Y, Suto A, Yonemori K, Kohno T, Shiraisihi K, Project BJ, Momozawa Y, Matsuda K, Iwasaki Y, Aoi T, Takata S, Murakami Y, Consortium NC, Kawai Y, Noiri E, Omae Y, Tokunaga K. Impact of germline variants on breast and ovarian cancer risk in Japanese women: an original cohort study and meta-analysis. EBioMedicine 116, 105758 (2025)

Yazaki S, Kitadai R, Momozawa Y, Yoshida T, Yamanaka T, Shiino S, Yamauchi C, Harano K, Saito M, Hirotsu Y, Aiba H, Hamamoto R, Shimizu C, Shimomura A, Shimoi T, Sudo K, Yoshida M, Sunami K, Shiraishi Y, Kuchiba A, Hori M, Katanoda K, Takata S, Ogawa A, Torasawa M, Mochizuki A, Shimada Y, Hiranuma K, Fujii E, Hirata M, Yamashita Y, Kogawa T, Murata T, Fujiwara S, Miyagi Y, Nakagomi H, Tachibana K, Matsuda K, Murakami Y, Tokunaga K, Kawai Y, Project BJ, Omata M, Ohtake T, Suto A, Onishi T, Naito Y, Yamashita T, Yonemori K, Kohno T, Shiraishi K. Germline variants of the POLH and RAD51 genes are candidate variants associated with risk of hormone receptor-negative young-onset breast cancer. NPJ Breast Cancer 11(1), 133 (2025)

Yokoyama Y, Takashina Y, Morel J, Taworntawat T, Kitamura N, Nagano U, Tanigaki T, Nakamura A, Miyazaki T, Taoka H, Mottis A, Perino A, Shinjo A, Suzuki N, Takekawa S, Fukuda S, Honda A, Ishihara K, Arita M, Tsubota K, Auwerx J, Watanabe M. Porphyran from discolored nori prevents metabolic syndrome through microbiota-bile acid-ceramide pathway. iScience 28(6), 112603 (2025)

Yonesaka K, Kurosaki T, Tanizaki J, Kawakami H, Tanaka K, Maenishi O, Takamura S, Sakai K, Chiba Y, Teramura T, Goto H, Otsuka E, Okida H, Funabashi M, Hashimoto Y, Hirotani K, Kamai Y, Kagari T, Nishio K, Kakimi K, Hayashi H. Chromosomal instability is associated with cGAS-STING activation in EGFR-TKI refractory non-small-cell lung cancer. Cells 14(6), 447 (2025)

Yoshida N, Stewart DR, Uchimura A, Arita K, Bombard Y, Frone M, Hinoi T, Kamiya K, Katamine S, Kayukawa J, Kodama K, Miller DT, Miura K, Muto K, Nagami F, Nakagawa H, Noda A, Ohishi W, Tanabe O, Terao C, Rajaraman P, Kato K, Biesecker LG. Symposium report‚ ethical and social considerations regarding return of secondary findings in atomic bomb survivors. Carcinogenesis 46(3), bgaf059 (2025)

Zang W, Koike Y, Nishimura K, Tanaka A, Yamazaki H, Yamasaki T, Ito H, Zhang Y, Aoyama Y, Saika W, Xiao M, Hasegawa C, Kunimoto H, Nakajima H, Ishikawa F, Takaori-Kondo A, Inoue D. BRD4 and MYB inhibition overcomes venetoclax resistance in EVI1-rearranged acute myeloid leukemia. Sci Rep 15(1), 37099 (2025)

Zhang B, Fagarasan S. Metabolism and metabolites regulating hematopoiesis. Curr Opin Immunol 93, 102525 (2025)

Zhang Y, Sakaue S, Morris S, Graff M, Yamamoto K, Chen Z, Li L, Keller MC, Goddard ME, Walters RG, Okada Y, Visscher PM, Yengo L. The contribution of gametic phase disequilibrium to the heritability of complex traits. Nat Genet 57(6), 1418-1425 (2025)

Zhao X, Zhao Q, Tanaka T. EpilepsyLLM: Fine-tuning large language models for Japanese epilepsy knowledge representation. Artificial Intelligence in Health (2025)

Zhao Y, Hisayoshi T, Zhang D, Suzuki S, Watanabe T, Kobayashi A, Guo Q, Momozawa Y, Shimokawa T, Kato S, Miki Y, Sunada S. Steroid-Modulated Transcription Synergistically Forms DNA Double-Strand Breaks With Topoisomerase II Inhibitor. Cancer Sci 116(7), 1952-1962 (2025)

Zheng W, Mowoe M, Hou W, Hagey DW, Imami K, Andaloussi SE. Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles. Adv Sci (Weinh) 13(12), e11414 (2025)